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Evidence-based GLP-1 & peptide discussion since 2023
ForumsRetatrutide & Triple AgonistsExpected approval timeline for retatrutide — my results so far Page 3

Expected approval timeline for retatrutide — my results so far

MariaRD Mon, Feb 23, 2026 at 10:30 AM 34 replies 955 viewsPage 3 of 7
Dr.ReproEndo
Senior Member
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Feb 24, 2026 at 11:33 PM#11
julia.endo said:
The useful move here is to separate what is established from what is widely repeated.

That holds where the measurement is reliable. Where it is noisy — and a lot of what gets tracked here is noisy — the same reasoning produces confident nonsense.

Ask again with the specifics and you will get a better answer than this one.

18 16mona_PHX, andrew_nyc, Dr.EndoEP and 15 others
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SleepFixSam
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Nov 2024
Hawaii
Feb 26, 2026 at 7:19 AM#12
dan_philly said:
The glucagon component looks paradoxical and is not.

Genuinely useful, thank you. I had the facts and not the framework.

19 17ingrid_STO, pete_nash, hank_denver and 16 others
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josh_phd_bmore
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Baltimore, MD
Feb 27, 2026 at 3:04 PM#13
julia.endo said:
The useful move here is to separate what is established from what is widely repeated.

I read this differently. The confidence in this thread is running ahead of the evidence, and I would rather the uncertainty were stated than smoothed over because it is unsatisfying.

20 18zoe_NC, Dr.ObesityLA, NurseKim_ATL and 17 others
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DoseLogDan
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Feb 2025
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Feb 28, 2026 at 10:49 PM#14

The figures, for anyone assembling their own picture. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.

21 19sophie_paris, mel_PDX, Dr.AddMedPHL and 18 others
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mike_mod
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Mar 2, 2026 at 6:34 AM#15

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. Thread quality here is what the rules are for. Keep it up.

22 20PurityPaulOR, MaxMetOK, MounjBrad and 19 others
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