🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsRetatrutide & Triple AgonistsTriple agonist sounds scary - is it actually safe — looking for input Page 3

Triple agonist sounds scary - is it actually safe — looking for input

Dr.PulmRoch Mon, Oct 27, 2025 at 9:12 PM 12 replies 1,132 viewsPage 3 of 3
mike.trainer_LA
Senior Member
1,567
7,234
Apr 2024
Los Angeles, CA
Oct 28, 2025 at 5:52 PM#11
SleepDoc_PDX said:
The version of this that has an answer is narrower than the version being asked.

That is correct as far as it goes, and here is where it stops going. Yes, and the corollary is less popular: if the reasoning holds, it also holds where it produces an answer we do not like.

7 5Dr.AddMedPHL, newstart_MO, mia_MS2 and 4 others
Reply Quote Save Share Report
LindaRN_retired
Member
189
890
Dec 2024
Sarasota, FL
Oct 29, 2025 at 3:59 AM#12
TirzTom said:
The phase 2 numbers were about 24% mean weight loss at 48 weeks on the top dose, with the curve still descending at the end of the study.

This answered a question I did not know how to ask.

Last edited: Oct 29, 2025 at 6:59 AM
8 6Dr.GutHealth, amsterdam_pete, LondonLisa and 5 others
Reply Quote Save Share Report
JessicaH_TX
Senior Member
4,123
13,456
Dec 2023
Houston, TX
Oct 29, 2025 at 2:06 PM#13
SleepDoc_PDX said:
The version of this that has an answer is narrower than the version being asked.

This is where I part company with the consensus forming above. Pushing back on the consensus forming here. Consistency is not the same as correctness, and a board that agrees with itself quickly is usually agreeing with the first person who sounded certain.

9 7kim_atl_prep, sarah_TO, wendy_avl and 6 others
Reply Quote Save Share Report

Janoshik Analytical — Independent Testing

Trusted third-party HPLC & mass spectrometry analysis. Verify peptide purity with the lab the community relies on. Independent. Accurate. Transparent.

Verify Your Peptides

GL Biochem (Shanghai) Ltd. — Direct Manufacturer

Est. 1998. The synthesis house behind the vials you send for testing. ISO 9001 and cGMP certified, 1,500+ staff, batch-specific COA with every order.

Browse GL Biochem
VendorMark
Senior Member
3,456
14,567
Jan 2024
Texas
Online
Oct 30, 2025 at 12:12 AM#14

One concrete data point for the thread. One practical note: write down what you did and when, before you need it. Reconstructing a timeline from memory three months later is how people end up unable to answer the one question that would have resolved it.

10 8Dr.PeteFamMed, claudia_zurich, nancy_portland and 7 others
Reply Quote Save Share Report
Admin
Administrator
2,456
9,812
Oct 2023
Online
Oct 30, 2025 at 10:18 AM#15

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again.

11 9PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 8 others
Reply Quote Save Share Report

Similar Threads

TRIUMPH-3 topline results — 24.2% body weight loss at 48 weeks10 replies
Retatrutide mechanism: GLP-1/GIP/glucagon triple agonism explained5 replies
Retatrutide Phase 2 dose-response analysis — optimal dose range10 replies
Glucagon receptor agonism and hepatic lipid oxidation — MASH implications13 replies
Retatrutide vs tirzepatide — dual vs triple agonist comparison22 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register