From the other side of the consultation, briefly. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.
Dr.RenalNash said:The mechanism and the magnitude are separate questions.
Same experience, arrived at from the opposite direction. Nothing to add that would improve it.
Dr.RenalNash said:The mechanism and the magnitude are separate questions.
Adding the part of the answer the thread has not reached. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.
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View ResultsThe figures, for anyone assembling their own picture. One habit that pays for itself: post the method alongside the number. A figure without its method cannot be checked, and an unchecked figure is how this community accumulates folklore.
Happy to go further on any of that.
Following on from Dr.RenalNash — and this may be the naive question:
What the dose-response curve actually looks like above 1.7mg, because the trial means hide how few people account for the extra loss?