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ForumsClinical Trials & ResearchMonthly semaglutide depot formulation — my results so far Page 5

Monthly semaglutide depot formulation — my results so far

tony_orlando Mon, Jul 22, 2024 at 3:23 PM 39 replies 2,686 viewsPage 5 of 8
Dr.RenalNash
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Jul 30, 2024 at 10:33 PM#21

From the other side of the consultation, briefly. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.

Last edited: Jul 31, 2024 at 3:33 AM
48 21wei_SG, cory_ATX, lori_vegas and 45 others
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Dr.EM_Chicago
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Aug 2, 2024 at 5:32 PM#22
Dr.RenalNash said:
The mechanism and the magnitude are separate questions.

Same experience, arrived at from the opposite direction. Nothing to add that would improve it.

Last edited: Aug 2, 2024 at 9:32 PM
49 22matt_MKE, Dr.ReproEndo, lucas_SP_BR and 46 others
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CarlaRPh_TPA
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Aug 5, 2024 at 12:30 PM#23
Dr.RenalNash said:
The mechanism and the magnitude are separate questions.

Adding the part of the answer the thread has not reached. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.

50 23BrianDallas92, labquiet_amy, emily_PDX and 47 others
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jason_paloalto
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Aug 8, 2024 at 7:26 AM#24

The figures, for anyone assembling their own picture. One habit that pays for itself: post the method alongside the number. A figure without its method cannot be checked, and an unchecked figure is how this community accumulates folklore.

Happy to go further on any of that.

1 24andrew_nyc
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Dr.MetabolicMD
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Aug 11, 2024 at 2:21 AM#25

Following on from Dr.RenalNash — and this may be the naive question:

What the dose-response curve actually looks like above 1.7mg, because the trial means hide how few people account for the extra loss?

Last edited: Aug 11, 2024 at 4:21 AM
2 0GenomicsKate, Dr.ObesityMed
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