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Evidence-based GLP-1 & peptide discussion since 2023
ForumsRetatrutide & Triple AgonistsRetatrutide nausea profile — looking for input Page 3

Retatrutide nausea profile — looking for input

Dr.CardioMD Wed, Jun 12, 2024 at 6:48 PM 17 replies 2,259 viewsPage 3 of 4
Dr.AddMedPHL
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Jun 16, 2024 at 7:03 PM#11
BariatricNurseD said:
The line between titrate-through and stop is not severity, it is trajectory and what else is present.

Fair, and it stops being fair at the extremes. The middle of the range is well understood; the ends are where the honest answer is that nobody knows.

34 7FitDadDave, RunnerRach, TrialNerd_Beth and 31 others
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marco_milano
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Jun 17, 2024 at 11:56 AM#12
zoe_NC said:
The glucagon component looks paradoxical and is not.

Genuinely useful, thank you. I had the facts and not the framework. Sending this to two other people who asked me the same thing last week.

35 8alex_tucson, kevin_tulsa, Dr.PainCLE and 32 others
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sophie_paris
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Jun 18, 2024 at 4:49 AM#13
BariatricNurseD said:
The line between titrate-through and stop is not severity, it is trajectory and what else is present.

I dislike how confidently this board tells people to push through. Incidence figures around 20 to 25% at the higher doses are class-typical, but the trials also had a discontinuation column, and "manageable with protocols" is not the same as manageable for everyone.

36 9MariaRD, AussieAnna, BethLabQueen and 33 others
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quinn_sf
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Jun 18, 2024 at 9:42 PM#14

One concrete data point for the thread. One practical note: write down what you did and when, before you need it. Reconstructing a timeline from memory three months later is how people end up unable to answer the one question that would have resolved it.

Last edited: Jun 19, 2024 at 3:42 AM
37 10andrew_nyc, Dr.EndoEP, GraceAZ_72 and 34 others
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mike_mod
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Jun 19, 2024 at 2:34 PM#15

Moderator note: a post naming a supplier has been edited. Discuss suppliers in the review sections, not here. Thread quality here is what the rules are for. Keep it up.

38 11PurityPaulOR, MaxMetOK, MounjBrad and 35 others
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