LindaRN_retired said:Four weeks is the pharmacokinetics, not caution.
No disagreement, though it depends on where somebody is starting from, and this thread has been assuming a starting point nobody stated.
tom_AK said:The glucagon component looks paradoxical and is not.
Saving this. It is the first explanation that did not require me to already understand it. Sending this to two other people who asked me the same thing last week.
LindaRN_retired said:Four weeks is the pharmacokinetics, not caution.
I disagree that the ladder is purely tolerability. The maintenance and regain data cluster at the top doses, so a ladder abandoned halfway leaves you outside the evidence base for the part that matters most — keeping it off.
Happy to go further on any of that.
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Browse GL BiochemThe figures, for anyone assembling their own picture. If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way. Most of the apparent contradictions in these threads dissolve at that step.
Moderator note: leaving this open. It is being argued well and the disagreement is the useful part.