JennaRN said:

Storage best practices for compounded storage and cold: Unreconstituted lyophilized powder: refrigerate (36-46°F), good for 12+ months Reconstituted…

Cold chain shipping for storage and cold: my last order arrived with the cold pack completely melted and the vial at room temperature. I contacted the vendor and they reshipped with better insulation.

What to look for in shipping: gel ice packs + insulated liner. If your peptide arrives warm, contact the vendor immediately. Don't assume it's still good.

Adding the numbers, since they settle part of this. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.

Ask again with the specifics and you will get a better answer than this one.

Dr.PeteFamMed said:

Cold chain shipping for storage and cold: my last order arrived with the cold pack completely melted and the vial at room temperature.

Adding the part of the answer the thread has not reached. Take it one variable at a time. Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent argument can untangle them after the fact.

A narrower follow-up, since the general answer is now clear:

How would you tell the difference between that and the alternative explanation?

Reporting back.

Update: the excursion was survivable and the vial was fine. I now keep a cheap fridge thermometer, which costs nothing and ends the argument.