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Evidence-based GLP-1 & peptide discussion since 2023
ForumsOther Peptides & Research CompoundsIpamorelin vs Tesamorelin — anyone have experience? Page 3

Ipamorelin vs Tesamorelin — anyone have experience?

pat_auckland Mon, Feb 2, 2026 at 6:26 PM 37 replies 1,157 viewsPage 3 of 8
LipidDoc_ATL
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Feb 3, 2026 at 9:31 AM#11
hans_munich said:
Semaglutide structural biology relevant to the pharmacology: semaglutide is a 31-amino acid peptide with 94% homology to native GLP-1(7-36).

No disagreement, though it depends on where somebody is starting from, and this thread has been assuming a starting point nobody stated.

7 5rachel_ABQ, traveltech_sara, AttorneyGrant and 4 others
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BiostatsBrad
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Feb 3, 2026 at 12:23 PM#12
mark_tokyo said:
The mechanism is more central than most summaries suggest.

Thank you — that is the clearest version of this I have read, and I have read a lot of them.

8 6Dr.BariatricHTX, LindaRN_retired, tommy_boulder and 5 others
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pete_nash
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Feb 3, 2026 at 3:15 PM#13
hans_munich said:
Semaglutide structural biology relevant to the pharmacology: semaglutide is a 31-amino acid peptide with 94% homology to native GLP-1(7-36).

I do not accept the framing. The question has been narrowed to the version that has a tidy answer, and the part that was dropped is the part the OP actually asked about.

Correct me if the detail matters more than I have assumed.

9 7mike_mod, SarahChen_PharmD, sarah.morrison and 6 others
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Dr.PathRoch
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Feb 3, 2026 at 6:07 PM#14

The figures, for anyone assembling their own picture. Keep the original post as written when you update it, and add the correction underneath. An edited-away mistake is invisible to the next person who makes it.

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Admin
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Feb 3, 2026 at 8:59 PM#15

Moderator note: a couple of off-topic posts removed. Thread quality here is what the rules are for. Keep it up.

11 9PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 8 others
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