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Evidence-based GLP-1 & peptide discussion since 2023
ForumsOther Peptides & Research CompoundsTB-500 for tissue repair — 12 month update Page 3

TB-500 for tissue repair — 12 month update

mel_PDX Tue, Nov 18, 2025 at 12:20 PM 27 replies 1,355 viewsPage 3 of 6
CarlaRPh_TPA
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Nov 23, 2025 at 4:09 PM#11
Dr.CardioMD said:
Receptor pharmacology relevant to the pharmacology: semaglutide is a GLP-1R agonist with a C-18 fatty acid chain that enables albumin binding (>99%),…

Fair, and it stops being fair at the extremes. The middle of the range is well understood; the ends are where the honest answer is that nobody knows.

Last edited: Nov 23, 2025 at 8:09 PM
19 17FDA_TrackerJim, ricardo_MIA, BrianDallas92 and 16 others
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wei_SG
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Nov 24, 2025 at 10:17 PM#12
JessicaM_2024 said:
The mechanism is more central than most summaries suggest.

Bookmarking. The distinction being drawn above is the one nobody else makes. Printing the relevant bit and taking it with me.

20 18SaraMom3, Dr.MetabolicMD, RetaRick_CA and 17 others
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Dr.BariatricHTX
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Nov 26, 2025 at 4:24 AM#13
Dr.CardioMD said:
Receptor pharmacology relevant to the pharmacology: semaglutide is a GLP-1R agonist with a C-18 fatty acid chain that enables albumin binding (>99%),…

Pushing back on Dr.CardioMD here. The counter-case has not been addressed. Somebody upthread described the situation that does not fit, and the thread moved on rather than engaging with it, which is the failure mode this board is supposed to avoid.

21 19Dr.EM_Chicago, pete_RVA, CarlaRPh_TPA and 18 others
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HPLC_Greg
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Nov 27, 2025 at 10:30 AM#14

One concrete data point for the thread. One habit that pays for itself: post the method alongside the number. A figure without its method cannot be checked, and an unchecked figure is how this community accumulates folklore.

22 20Dr.MetabolicMD, RetaRick_CA, JenPlateau and 19 others
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mike_mod
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Nov 28, 2025 at 4:36 PM#15

Moderator note: the sourcing question belongs in the vendor section and has been split out. No action needed from anybody.

Last edited: Nov 28, 2025 at 6:36 PM
23 21PurityPaulOR, MaxMetOK, MounjBrad and 20 others
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