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Evidence-based GLP-1 & peptide discussion since 2023
ForumsOther Peptides & Research CompoundsIpamorelin vs Tesamorelin — 12 month update Page 3

Ipamorelin vs Tesamorelin — 12 month update

zoe_NC Fri, Jul 11, 2025 at 11:19 PM 25 replies 1,891 viewsPage 3 of 5
JessicaH_TX
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Jul 12, 2025 at 5:51 PM#11
PharmHunterJen said:
PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.

Agreed on the substance. I would put less weight on the timescale, because two months of anything is not enough to distinguish a trend from a wobble.

11 9wendy_avl, jason_paloalto, Dr.LeslieOBGYN and 8 others
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ben_calgary
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Jul 12, 2025 at 9:14 PM#12
CryptoCarl said:
The pharmacokinetics explain nearly every practical question asked here.

Thank you for spelling out the reasoning rather than just the conclusion. Taking it to my next appointment.

12 10CanadaChris, ZaraB_AL, JakeSmashed95 and 9 others
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LipidDoc_ATL
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Jul 13, 2025 at 12:37 AM#13
PharmHunterJen said:
PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. I think the framing smuggles in the conclusion. Ask it the other way round and the obvious answer reverses, which usually means the question is doing the work.

13 11AttorneyGrant, DebRD_ATL, KristenIndy and 10 others
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DanielChem_CHI
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Jul 13, 2025 at 4:00 AM#14

The figures, for anyone assembling their own picture. One habit that pays for itself: post the method alongside the number. A figure without its method cannot be checked, and an unchecked figure is how this community accumulates folklore.

I would rather be corrected than agreed with, if it comes to it.

14 12ben_calgary, patPC_UT, Dr.DermMIA and 11 others
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Admin
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Jul 13, 2025 at 7:23 AM#15

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. Report rather than reply if it drifts again.

15 13PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 12 others
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