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Evidence-based GLP-1 & peptide discussion since 2023
ForumsProgress & Lab Results12-month metabolic panel comparison — before and after GLP-1 Page 2

12-month metabolic panel comparison — before and after GLP-1

DataDave Mon, Jun 8, 2026 at 4:31 PM 22 replies 610 viewsPage 2 of 5
NeuroNate
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Jun 8, 2026 at 4:32 PM#6
pete_manc_UK said:
Quarterly for the first year is convention rather than evidence, and it is defensible for a simple reason: it is roughly the interval over which HbA1c…

This is where I part company with the consensus forming above. I would drop the "get everything" instinct further than this thread does. Every extra test is another chance at a false positive, and incidental findings have their own cost in scans, biopsies and worry.

Last edited: Jun 8, 2026 at 10:32 PM
9 4jason_paloalto, Dr.LeslieOBGYN, MikeNYC_runner and 6 others
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dan_philly
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Philadelphia, PA
Jun 8, 2026 at 4:32 PM#7
DataDave said:
I got a full panel before starting and a repeat at three months, and the second one is more useful than the first purely because I now have something…

Blood work came back perfect. baseline bloodwork + this community = winning. 🏆

8 3AmyNC_wife, SkepticalSean, Dr.CardioMD and 5 others
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EndoResFellow
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Baltimore, MD
Jun 8, 2026 at 4:33 PM#8
NeuroNate said:
I would drop the "get everything" instinct further than this thread does.

PSA: get baseline labs BEFORE starting baseline bloodwork therapy. You need a "before" picture to measure progress. My recommended pre-treatment panel:

  1. CMP + A1C + fasting insulin
  2. Complete lipid panel with particle count if possible
  3. hsCRP, ferritin, B12, vitamin D
  4. Thyroid panel (TSH + free T4)
  5. CBC with differential
  6. Liver panel (ALT, AST, GGT)
  7. DEXA scan or body composition

Total cost at Quest without insurance: ~$200. Worth every penny for the data.

Last edited: Jun 8, 2026 at 6:33 PM
7 2paul_denver, TinaHashiRN, robert_kc and 4 others
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sarah_nash92
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Jun 2024
Nashville, TN
Jun 8, 2026 at 4:33 PM#9

One thing that is still open after dave_SLC’s answer:

What actually belongs on a baseline panel, as opposed to the enormous list that gets pasted around here?

Last edited: Jun 8, 2026 at 10:33 PM
6 1CanadaChris, ZaraB_AL, JakeSmashed95 and 3 others
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DataDave
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Washington
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Jun 8, 2026 at 4:35 PM#10

Reporting back.

Took the whole panel in rather than the one flagged line, and the conversation lasted two minutes instead of generating three more tests.

20 18Dr.GutHealth, amsterdam_pete, LondonLisa and 17 others
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