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ForumsSide Effects & ManagementKidney stone risk on GLP-1 — dehydration and oxalate concerns Page 3

Kidney stone risk on GLP-1 — dehydration and oxalate concerns

Dr.NateNeph Sun, May 17, 2026 at 11:50 AM 14 replies 456 viewsPage 3 of 3
VanRx_Mike
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May 19, 2026 at 11:28 PM#11
hans_munich said:
FLOW is the relevant trial and it reported a meaningful reduction in kidney-disease progression and related death in people with type 2 diabetes and…

Genuinely useful, thank you. I had the facts and not the framework.

Last edited: May 20, 2026 at 2:28 AM
43 16Dr.LeslieOBGYN, MikeNYC_runner and 40 others
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PharmacoVig_BOS
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May 20, 2026 at 1:37 AM#12

From the other side of the consultation, briefly. The version of this that has an answer is narrower than the version being asked. Narrow it and it becomes tractable; leave it broad and the thread will produce nine confident and incompatible replies.

44 17Dr.GutHealth, amsterdam_pete, LondonLisa and 41 others
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mike.trainer_LA
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May 20, 2026 at 3:46 AM#13
JenPlateau said:
Electrolyte monitoring on hydration — especially important during early titration when GI effects are most pronounced: Sodium: 139 mEq/L (normal, but…

Pushing back on JenPlateau here. The counter-case has not been addressed. Somebody upthread described the situation that does not fit, and the thread moved on rather than engaging with it, which is the failure mode this board is supposed to avoid.

45 18mia_MS2, LeilaHI, marcus_mpls and 42 others
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HPLC_Greg
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May 20, 2026 at 5:55 AM#14

One concrete data point for the thread. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.

Last edited: May 20, 2026 at 11:55 AM
46 19Dr.MetabolicMD, RetaRick_CA, JenPlateau and 43 others
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mike_mod
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May 20, 2026 at 8:04 AM#15

Moderator note: the sourcing question belongs in the vendor section and has been split out. Thread quality here is what the rules are for. Keep it up.

47 20PurityPaulOR, MaxMetOK, MounjBrad and 44 others
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