🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsMASH / Liver DiseaseHas anyone dealt with de novo lipogenesis reduction on glp-1? Page 3

Has anyone dealt with de novo lipogenesis reduction on glp-1?

NurseLeah_Nash Tue, Nov 18, 2025 at 1:33 AM 34 replies 1,698 viewsPage 3 of 7
BenResearch_OR
Senior Member
2,456
11,234
Dec 2023
Oregon
Nov 23, 2025 at 12:06 PM#11
Dr.LeslieOBGYN said:
The useful move here is to separate what is established from what is widely repeated.

That is right, and it stops being right at the edges. The general case is well behaved; the interesting cases in this thread are all at the boundary where the general case breaks.

15 13julia.endo, JessicaM_2024, TomFromTexas and 12 others
Reply Quote Save Share Report
jason_sac26
New Member
34
123
Jan 2026
Sacramento, CA
Nov 23, 2025 at 2:53 PM#12
rick_sfbay said:
NASH/MAFLD therapeutic landscape and liver and MASH: GLP-1 agonists are emerging as potential first-line NASH therapy.

Thank you for spelling out the reasoning rather than just the conclusion. Printing the relevant bit and taking it with me.

16 14Dr.EM_Chicago, pete_RVA, CarlaRPh_TPA and 13 others
Reply Quote Save Share Report
Dr.GutHealth
Senior Member
1,456
7,890
Mar 2024
Minnesota
Nov 23, 2025 at 5:40 PM#13
Dr.LeslieOBGYN said:
The useful move here is to separate what is established from what is widely repeated.

I do not accept the framing. The question has been narrowed to the version that has a tidy answer, and the part that was dropped is the part the OP actually asked about.

17 15jennifer_SEA, tyler_CSCS, VanRx_Mike and 14 others
Reply Quote Save Share Report

Janoshik Analytical — Independent Testing

Trusted third-party HPLC & mass spectrometry analysis. Verify peptide purity with the lab the community relies on. Independent. Accurate. Transparent.

Verify Your Peptides

GL Biochem (Shanghai) Ltd. — Direct Manufacturer

Est. 1998. The synthesis house behind the vials you send for testing. ISO 9001 and cGMP certified, 1,500+ staff, batch-specific COA with every order.

Browse GL Biochem
FDA_TrackerJim
Senior Member
1,567
7,890
Feb 2024
Rockville, MD
Nov 23, 2025 at 8:27 PM#14

One concrete data point for the thread. Keep the original post as written when you update it, and add the correction underneath. An edited-away mistake is invisible to the next person who makes it.

18 16Dr.LeslieOBGYN, MikeNYC_runner and 15 others
Reply Quote Save Share Report
mike_mod
Moderator
7,234
19,823
Nov 2023
New York
Online
Nov 23, 2025 at 11:14 PM#15

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again. Carry on.

19 17PurityPaulOR, MaxMetOK, MounjBrad and 16 others
Reply Quote Save Share Report

Similar Threads

Survodutide MASH Phase 2b — histological improvement data9 replies
Semaglutide and MASH — liver fat reduction quantification13 replies
Non-invasive MASH biomarkers — FibroScan, ELF, FIB-4 on GLP-110 replies
ALT normalization rates on GLP-1 — pooled trial data20 replies
GLP-1 hepatoprotection — direct vs indirect mechanisms16 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register