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ForumsMASH / Liver DiseaseHas anyone dealt with de novo lipogenesis reduction on glp-1? Page 6

Has anyone dealt with de novo lipogenesis reduction on glp-1?

NurseLeah_Nash Tue, Nov 18, 2025 at 1:33 AM 34 replies 1,698 viewsPage 6 of 7
TrialTracker_MD
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Nov 26, 2025 at 10:38 AM#26

The figures, for anyone assembling their own picture. For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine. Half the figures circulating in this community trace back to a secondary summary that dropped a qualifier.

Last edited: Nov 26, 2025 at 3:38 PM
1 24Dr.EM_Chicago
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NurseAsh_DET
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Nov 26, 2025 at 7:11 PM#27

Following on from KevinCompounds — and this may be the naive question:

What would you measure differently if you were starting again?

2 0ricardo_MIA, BrianDallas92
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JenPlateau
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Nov 27, 2025 at 3:44 AM#28
TrialTracker_MD said:
For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine.

Careful with the causal language. Two things moving together in a period when five things changed is not a mechanism, and stating it as one makes the thread less useful to somebody reading it later.

3 1RunnerRach, TrialNerd_Beth, HPLC_Greg
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TirzTom
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Nov 27, 2025 at 12:17 PM#29
TrialTracker_MD said:
For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine.

Correct as far as it goes. The part it does not cover is what to do when the honest answer is "not enough data", which is more often than anyone likes.

4 2SandraNC_45, Dr.EndoIndy, tom_AK and 1 other
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NurseLeah_Nash
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Nov 27, 2025 at 8:50 PM#30

OP back with an update, since a thread like this is useless without one.

Reporting back for the archive rather than for the thread: I did the narrow version of what was suggested, gave it the full interval, and it settled. Posting it because threads without a follow-up are half a thread.

26 24Dr.NateNeph, PharmD_Rodriguez, julia.endo and 23 others
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