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ForumsMASH / Liver DiseaseFibrosis regression on GLP-1 — looking for input Page 3

Fibrosis regression on GLP-1 — looking for input

oliver_london Mon, Nov 10, 2025 at 9:38 PM 23 replies 1,403 viewsPage 3 of 5
maya_sedona
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Nov 15, 2025 at 12:00 AM#11
PharmD_Rodriguez said:
Liver imaging follow-up for liver and MASH: FibroScan at baseline showed CAP score 326 dB/m (moderate steatosis) and stiffness 10.8 kPa (possible…

Thank you for spelling out the reasoning rather than just the conclusion.

19 17wanda_boise, NurseAsh_DET, BenResearch_OR and 16 others
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MASHdoc_SA
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Nov 16, 2025 at 5:57 AM#12

Clinical perspective, offered as context rather than as advice. Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the correction. That is slower than asserting, and it is the only version that survives being wrong.

20 18TrialTracker_MD, JennaRN, LabKate and 17 others
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Dr.GutHealth
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Nov 17, 2025 at 11:54 AM#13
rachel_ABQ said:
ATTAIN trial (survodutide) context for liver and MASH: survodutide, a GLP-1/glucagon dual agonist, showed -18.7% body weight at 46 weeks in the Phase…

Pushing back on rachel_ABQ here. The objection nobody has made: this only works if the measurement is doing what we assume it is doing, and that assumption has not been tested here.

21 19jennifer_SEA, tyler_CSCS, VanRx_Mike and 18 others
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NicoleRaleigh
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Nov 18, 2025 at 5:50 PM#14

The figures, for anyone assembling their own picture. Worth stating the units and the reference range whenever you post a number here. A large fraction of the apparent disagreement in these threads is two people using different units and both being right.

22 20VendorMark, COA_Karl, MikeFit_NJ and 19 others
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mike_mod
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Nov 19, 2025 at 11:46 PM#15

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source. Report rather than reply if it drifts again.

Last edited: Nov 20, 2025 at 1:46 AM
23 21PurityPaulOR, MaxMetOK, MounjBrad and 20 others
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