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Evidence-based GLP-1 & peptide discussion since 2023
ForumsProgress & Lab Results[PREMIUM] 6-month face transformation — dermatology perspective with before/after

[PREMIUM] 6-month face transformation — dermatology perspective with before/after

Dr.DermMIA Fri, Apr 24, 2026 at 3:56 AM 34 replies 756 viewsPage 1 of 7
Dr.DermMIA
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Miami, FL
Apr 24, 2026 at 3:56 AM#1

Thirteen weeks at the same dose with no change on the scale, and I have gone from assuming it was the drug to assuming it was me and back several times.

What I am trying to establish is how to distinguish a genuine plateau from measurement noise and creeping intake, before changing anything.

Not looking for reassurance. Looking for the part I have got wrong.

43 13LipidDoc_ATL, BariatricNurseD, MASHdoc_SA and 40 others
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Dr.SleepRoch
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Apr 2024
Rochester, MN
Apr 24, 2026 at 5:17 AM#2
Dr.DermMIA said:
Thirteen weeks at the same dose with no change on the scale, and I have gone from assuming it was the drug to assuming it was me and back several…

Plateau breaking story with a stall: I stalled at 204 lbs for 5 weeks. Tried everything — calorie cycling, increased exercise, more water. Nothing worked.

What finally broke the plateau: switching from evening to morning injection. Lost 7 lbs in the next 2 weeks. Plateaus are temporary — they always break if you stay consistent.

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PeptideSynthNJ
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Aug 2024
Princeton, NJ
Apr 24, 2026 at 6:38 AM#3
Dr.SleepRoch said:
Plateau breaking story with a stall: I stalled at 204 lbs for 5 weeks.

That is correct as far as it goes, and here is where it stops going. Most reported plateaus are not plateaus. Weight is a noisy signal — daily variation of one to two kilograms from glycogen, sodium and gut contents — so a fortnight of flat readings is well inside the noise band. Before concluding anything, look at a rolling weekly average over at least four weeks and at a tape measure, because recomposition shows up in circumference before it shows up in weight. Then track intake honestly for a week: appetite suppression fades unevenly, and intake creeping back up is the single commonest cause.

Last edited: Apr 24, 2026 at 10:38 AM
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sarah_TO
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Sep 2024
Toronto, CA
Apr 24, 2026 at 7:59 AM#4
Dr.DermMIA said:
Thirteen weeks at the same dose with no change on the scale, and I have gone from assuming it was the drug to assuming it was me and back several…

Same experience, arrived at from the opposite direction. The detail I would add is minor and it is already implied above.

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TinaHashiRN
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Sep 2024
Raleigh, NC
Apr 24, 2026 at 3:51 PM#5

Clinical perspective, offered as context rather than as advice. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.

Last edited: Apr 24, 2026 at 9:51 PM
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