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Evidence-based GLP-1 & peptide discussion since 2023
ForumsProgress & Lab ResultsNot losing weight but my clothes fit different?? Explain

Not losing weight but my clothes fit different?? Explain

SaraMom3 Mon, Feb 23, 2026 at 7:31 PM 11 replies 980 viewsPage 1 of 3
SaraMom3
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Aug 2024
Ohio
Feb 23, 2026 at 7:31 PM#1

Thirteen weeks at the same dose with no change on the scale, and I have gone from assuming it was the drug to assuming it was me and back several times.

What would genuinely help is knowing how to distinguish a genuine plateau from measurement noise and creeping intake, before changing anything.

Practical detail welcome, however dull — the duller the better.

21 16BethLabQueen, ChrisMacros, KetoKyle and 18 others
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LarryQC_SD
Senior Member
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Jan 2024
San Diego, CA
Feb 23, 2026 at 8:31 PM#2
SaraMom3 said:
Thirteen weeks at the same dose with no change on the scale, and I have gone from assuming it was the drug to assuming it was me and back several…

Plateau breaking story with a stall: I stalled at 216 lbs for 6 weeks. Tried everything — calorie cycling, increased exercise, more water. Nothing worked.

What finally broke the plateau: increasing protein to 150g/day. Lost 9 lbs in the next 2 weeks. Plateaus are temporary — they always break if you stay consistent.

20 15paul_denver, TinaHashiRN, robert_kc and 17 others
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AmyNC_wife
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Jun 2024
North Carolina
Feb 23, 2026 at 9:31 PM#3
LarryQC_SD said:
Plateau breaking story with a stall: I stalled at 216 lbs for 6 weeks.

That is correct as far as it goes, and here is where it stops going. Genuine plateaus happen too, and the mechanism is metabolic adaptation plus a smaller body. A body 20kg lighter needs meaningfully fewer calories at rest and less to move, so the deficit that produced the first phase is arithmetically smaller now. The options are the honest ones — increase the deficit slightly, increase activity, or accept the new plateau — and escalating the dose is only one of them.

19 14PharmD_Rodriguez, julia.endo, JessicaM_2024 and 16 others
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Dr.NephBHM_UK
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Jun 2024
Birmingham, UK
Feb 23, 2026 at 10:31 PM#4
SaraMom3 said:
Thirteen weeks at the same dose with no change on the scale, and I have gone from assuming it was the drug to assuming it was me and back several…

Can confirm. Same sequence, different timescale.

18 13SurmountFan_IN, PeptideChemSF, A1cHero_PHX and 15 others
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newstart_MO
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Feb 2026
Springfield, MO
Feb 24, 2026 at 4:13 AM#5

From the other side of the consultation, briefly. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.

Last edited: Feb 24, 2026 at 10:13 AM
17 12RunnerRach, TrialNerd_Beth, HPLC_Greg and 14 others
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