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Evidence-based GLP-1 & peptide discussion since 2023
ForumsMASH / Liver DiseaseHas anyone dealt with fibrosis regression on glp-1? Page 5

Has anyone dealt with fibrosis regression on glp-1?

JenMemphis Sat, Apr 26, 2025 at 7:21 PM 46 replies 1,810 viewsPage 5 of 10
NurseLeah_Nash
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May 1, 2025 at 11:36 PM#21
hank_denver said:
Say what you would expect to see if you were wrong, before you look.

I read this differently. The confidence in this thread is running ahead of the evidence, and I would rather the uncertainty were stated than smoothed over because it is unsatisfying.

Last edited: May 2, 2025 at 12:36 AM
39 12RegAffairsDC, BiostatsBrad, PeptideSynthNJ and 36 others
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mike_nyc
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May 2, 2025 at 6:50 PM#22
hank_denver said:
Say what you would expect to see if you were wrong, before you look.

True, and it depends on a baseline nobody has stated. Without knowing where someone started, the same number can be an excellent result or a disappointing one.

40 13stefan_berlin, Dr.EM_Chicago, pete_RVA and 37 others
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ricardo_MIA
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May 3, 2025 at 2:04 PM#23
hank_denver said:
Say what you would expect to see if you were wrong, before you look.

That reframing is the part I needed. I will report back once I have actually tried it.

Last edited: May 3, 2025 at 7:04 PM
41 14CanadaChris, ZaraB_AL, JakeSmashed95 and 38 others
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Dr.KarenChen
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May 4, 2025 at 9:19 AM#24

Clinical perspective, offered as context rather than as advice. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

42 15mike.trainer_LA, sarah_nash92, FitDadDave and 39 others
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ben_calgary
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May 5, 2025 at 4:34 AM#25
Dr.KarenChen said:
There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

Second this. Nothing to add that would improve it.

Last edited: May 5, 2025 at 10:34 AM
43 16NauseaFreeNow, SteveThurs, B12Beth and 40 others
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