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Evidence-based GLP-1 & peptide discussion since 2023
ForumsSide Effects & ManagementWhen to stop GLP-1 — need advice Page 8

When to stop GLP-1 — need advice

pam_stl Mon, Oct 20, 2025 at 2:04 AM 39 replies 1,952 viewsPage 8 of 8
B12Beth
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Maryland
Dec 3, 2025 at 12:58 AM#36
SarahChen_PharmD said:
It is worth asking what the claim would look like if it were false.

There is a second half to this that has not been said yet. The version of this that has an answer is narrower than the version being asked. Narrow it and it becomes tractable; leave it broad and the thread will produce nine confident and incompatible replies.

If somebody has the primary source to hand I would rather cite it than paraphrase it.

11 9GraceAZ_72, carl_compliance, DanielChem_CHI and 8 others
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bri_stats
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Seattle, WA
Dec 5, 2025 at 9:39 AM#37

The figures, for anyone assembling their own picture. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

Last edited: Dec 5, 2025 at 1:39 PM
12 10mike.trainer_LA, sarah_nash92, FitDadDave and 9 others
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newstart_MO
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Springfield, MO
Dec 7, 2025 at 6:21 PM#38

One thing that is still open after SarahChen_PharmD’s answer:

Did your prescriber agree with that reading, and if not what was their objection?

Last edited: Dec 8, 2025 at 12:21 AM
13 11HPLC_Greg, LibrarianMeg, bri_stats and 10 others
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MikeKY_noInsulin
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Oct 2024
Louisville, KY
Dec 10, 2025 at 3:05 AM#39
bri_stats said:
If you are going to change something, change one thing and give it long enough to express itself.

I do not accept the framing. The question has been narrowed to the version that has a tidy answer, and the part that was dropped is the part the OP actually asked about.

14 12amy_econ_NJ, bbq_ray_KC, oliver_london and 11 others
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JennaRN
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Dec 12, 2025 at 11:50 AM#40
bri_stats said:
If you are going to change something, change one thing and give it long enough to express itself.

True, and it depends on a baseline nobody has stated. Without knowing where someone started, the same number can be an excellent result or a disappointing one.

36 9SleepDoc_PDX, RegAffairsDC, BiostatsBrad and 33 others
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