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ForumsSide Effects & ManagementHypoglycemia risk with concomitant sulfonylurea use — 6 month update Page 3

Hypoglycemia risk with concomitant sulfonylurea use — 6 month update

PharmacoVig_BOS Sun, May 25, 2025 at 10:17 PM 15 replies 1,495 viewsPage 3 of 3
Dr.GastroMayo
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May 29, 2025 at 9:10 PM#11
DeniseRN_TPA said:
The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.

That is right for the common case. Whether it is right for the case being asked about depends on a detail that has not been given.

Last edited: May 30, 2025 at 2:10 AM
27 0mike_nyc, VendorMark, COA_Karl and 24 others
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MeganSA_TX
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May 29, 2025 at 11:58 PM#12
EndoResFellow said:
Agreed on adaptation, with a caveat: adaptation applies to gastric emptying and not to everything.

Genuinely useful, thank you. I had the facts and not the framework.

Last edited: May 30, 2025 at 1:58 AM
28 1julia.endo, JessicaM_2024, TomFromTexas and 25 others
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SleepDoc_PDX
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May 30, 2025 at 2:46 AM#13
DeniseRN_TPA said:
The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.

Worth saying that the confident version of this is more useful to the person writing it than to the person reading it.

Last edited: May 30, 2025 at 5:46 AM
29 2carlos_SATX, sophie_paris, mel_PDX and 26 others
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VendorMark
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May 30, 2025 at 5:34 AM#14

Adding the numbers, since they settle part of this. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

Last edited: May 30, 2025 at 7:34 AM
30 3Dr.PeteFamMed, claudia_zurich, nancy_portland and 27 others
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mike_mod
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May 30, 2025 at 8:22 AM#15

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again. Thread quality here is what the rules are for. Keep it up.

31 4PurityPaulOR, MaxMetOK, MounjBrad and 28 others
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