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Evidence-based GLP-1 & peptide discussion since 2023
ForumsProgress & Lab Results[PREMIUM] From wheelchair-bound to hiking again — what worked for you?

[PREMIUM] From wheelchair-bound to hiking again — what worked for you?

FDA_TrackerJim Tue, Jul 29, 2025 at 12:21 PM 13 replies 1,404 viewsPage 1 of 3
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FDA_TrackerJim
Senior Member
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Feb 2024
Rockville, MD
Jul 29, 2025 at 12:21 PM#1

Thirteen weeks at the same dose with no change on the scale, and I have gone from assuming it was the drug to assuming it was me and back several times.

The bit I cannot resolve on my own is how to distinguish a genuine plateau from measurement noise and creeping intake, before changing anything.

Not looking for reassurance. Looking for the part I have got wrong.

31 1Dr.Martinez, mike_mod, SarahChen_PharmD and 28 others
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CarlaRPh_TPA
Senior Member
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Jan 2024
Tampa, FL
Jul 29, 2025 at 12:26 PM#2
FDA_TrackerJim said:
Thirteen weeks at the same dose with no change on the scale, and I have gone from assuming it was the drug to assuming it was me and back several…

Plateau breaking story with a stall: I stalled at 216 lbs for 8 weeks. Tried everything — calorie cycling, increased exercise, more water. Nothing worked.

What finally broke the plateau: adding HIIT cardio 2x/week. Lost 6 lbs in the next 3 weeks. Plateaus are temporary — they always break if you stay consistent.

30 0ricardo_MIA, BrianDallas92, labquiet_amy and 27 others
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wei_SG
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Nov 2024
Singapore, SG
Jul 29, 2025 at 12:31 PM#3
CarlaRPh_TPA said:
Plateau breaking story with a stall: I stalled at 216 lbs for 8 weeks.

No disagreement with CarlaRPh_TPA. One condition attached. Most reported plateaus are not plateaus. Weight is a noisy signal — daily variation of one to two kilograms from glycogen, sodium and gut contents — so a fortnight of flat readings is well inside the noise band. Before concluding anything, look at a rolling weekly average over at least four weeks and at a tape measure, because recomposition shows up in circumference before it shows up in weight. Then track intake honestly for a week: appetite suppression fades unevenly, and intake creeping back up is the single commonest cause.

29 24Dr.MetabolicMD, RetaRick_CA, JenPlateau and 26 others
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JenPlateau
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Nov 2024
Missouri
Jul 29, 2025 at 12:36 PM#4
FDA_TrackerJim said:
Thirteen weeks at the same dose with no change on the scale, and I have gone from assuming it was the drug to assuming it was me and back several…

Can confirm. Same sequence, different timescale.

28 23FitDadDave, RunnerRach, TrialNerd_Beth and 25 others
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EndoResFellow
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Sep 2024
Baltimore, MD
Jul 29, 2025 at 1:02 PM#5

Clinical perspective, offered as context rather than as advice. Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third retelling.

27 22Dr.ObesityLA, NurseKim_ATL, paul_denver and 24 others
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