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ForumsMASH / Liver DiseaseEfinopegdutide MASH data — July 2024 Page 8

Efinopegdutide MASH data — July 2024

KarenAZ_mom Thu, May 30, 2024 at 2:14 PM 39 replies 2,830 viewsPage 8 of 8
Dr.PainCLE
Senior Member
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Cleveland, OH
Sep 1, 2024 at 12:41 PM#36
josh_phd_bmore said:
The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…

Thank you — that is the clearest version of this I have read, and I have read a lot of them. Sending this to two other people who asked me the same thing last week.

14 12Dr.PathRoch, mona_PHX, andrew_nyc and 11 others
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Dr.SurgeonPGH
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Mar 2024
Pittsburgh, PA
Sep 6, 2024 at 5:18 PM#37

From the other side of the consultation, briefly. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.

15 13TomTeleRx, DoseLogDan, SleepFixSam and 12 others
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Dr.GastroMayo
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Mayo Clinic, MN
Sep 11, 2024 at 9:52 PM#38
Dr.SurgeonPGH said:
The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.

Can confirm. Same sequence, different timescale.

16 14COA_Karl, MikeFit_NJ, InsuranceTom and 13 others
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jason_paloalto
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Nov 2024
Palo Alto, CA
Sep 17, 2024 at 2:23 AM#39
Dr.SurgeonPGH said:
The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.

Coming at Dr.SurgeonPGH’s question from a different direction. It is worth asking what the claim would look like if it were false. If nothing would look different, it is not a claim about the world and no amount of discussion will settle it.

17 15andrew_nyc, Dr.EndoEP, GraceAZ_72 and 14 others
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dave_SLC
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Aug 2024
Salt Lake City, UT
Sep 22, 2024 at 6:51 AM#40

One concrete data point for the thread. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

39 12Dr.BariatricHTX, LindaRN_retired, tommy_boulder and 36 others
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