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Evidence-based GLP-1 & peptide discussion since 2023
ForumsProgress & Lab Results[PREMIUM] T2D reversal complete dataset — what worked for you?

[PREMIUM] T2D reversal complete dataset — what worked for you?

CarlaRPh_TPA Thu, May 15, 2025 at 6:57 PM 15 replies 1,511 viewsPage 1 of 3
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CarlaRPh_TPA
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May 15, 2025 at 6:57 PM#1

Thirteen weeks at the same dose with no change on the scale, and I have gone from assuming it was the drug to assuming it was me and back several times.

What I actually want to know is how to distinguish a genuine plateau from measurement noise and creeping intake, before changing anything.

Practical detail welcome, however dull — the duller the better.

8 3FDA_TrackerJim, ricardo_MIA, BrianDallas92 and 5 others
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SarahChen_PharmD
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May 15, 2025 at 7:40 PM#2
CarlaRPh_TPA said:
Thirteen weeks at the same dose with no change on the scale, and I have gone from assuming it was the drug to assuming it was me and back several…

Plateau breaking story with a stall: I stalled at 201 lbs for 7 weeks. Tried everything — calorie cycling, increased exercise, more water. Nothing worked.

What finally broke the plateau: a brief dose increase followed by return to maintenance. Lost 12 lbs in the next 3 weeks. Plateaus are temporary — they always break if you stay consistent.

Last edited: May 15, 2025 at 10:40 PM
7 2NurseKim_ATL, paul_denver, TinaHashiRN and 4 others
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MASHdoc_SA
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May 15, 2025 at 8:23 PM#3
SarahChen_PharmD said:
Plateau breaking story with a stall: I stalled at 201 lbs for 7 weeks.

Agreeing with SarahChen_PharmD, and the qualification matters more than the agreement. Most reported plateaus are not plateaus. Weight is a noisy signal — daily variation of one to two kilograms from glycogen, sodium and gut contents — so a fortnight of flat readings is well inside the noise band. Before concluding anything, look at a rolling weekly average over at least four weeks and at a tape measure, because recomposition shows up in circumference before it shows up in weight. Then track intake honestly for a week: appetite suppression fades unevenly, and intake creeping back up is the single commonest cause.

That is the short version; the long version is somebody else's post.

Last edited: May 15, 2025 at 11:23 PM
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MariaRD
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May 15, 2025 at 9:06 PM#4
CarlaRPh_TPA said:
Thirteen weeks at the same dose with no change on the scale, and I have gone from assuming it was the drug to assuming it was me and back several…

This matches mine closely enough to be worth saying so out loud.

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Dr.GastroMayo
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May 16, 2025 at 1:08 AM#5

Adding the clinical framing, because it changes how the question reads. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.

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