jim_asheville said:

Site reactions are usually technique or temperature rather than the material.

Injection site reactions and injection-site reactions: I was getting red, itchy welts at every injection site that lasted 3-4 days. Turned out I was allergic to the alcohol swab, not the medication!

Switched to chlorhexidine prep pads and the reaction stopped completely. If you're having persistent injection site reactions, consider this possibility before blaming the drug.

jim_asheville said:

Site reactions are usually technique or temperature rather than the material.

Helpful tip for injection-site reactions needle anxiety: ice the injection site for 30 seconds before injecting. You'll barely feel the 30g needle go in. I went from dreading injection day to not even flinching.

Also, don't watch the needle enter your skin. Look away, take a deep breath, and it's over in seconds.

Dr.PeteFamMed said:

Helpful tip for injection-site reactions needle anxiety: ice the injection site for 30 seconds before injecting.

For those on injection-site reactions — a practical guide to injection site rotation. I use a 4-site system:

• Week 1: Right abdomen (2 inches from navel)
• Week 2: Left abdomen
• Week 3: Right thigh (outer, middle third)
• Week 4: Left thigh

Then repeat. This gives each site 4 weeks to recover. I mark it in my phone calendar so I never inject the same area two weeks in a row.

Dr.NateNeph said:

Injection site reactions and injection-site reactions: I was getting red, itchy welts at every injection site that lasted 3-4 days.

Same experience, arrived at from the opposite direction. I had assumed I was the exception until I read this.