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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCOA & Analytical TestingLC-MS/MS vs HPLC for peptide analysis — November 2025 Page 6

LC-MS/MS vs HPLC for peptide analysis — November 2025

HealthEcon_DC Tue, Nov 18, 2025 at 8:01 PM 29 replies 1,356 viewsPage 6 of 6
NurseKim_ATL
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Nov 23, 2025 at 4:52 AM#26

From the other side of the consultation, briefly. The useful move here is to separate what is established from what is widely repeated. Those two sets overlap less than the confident tone of most write-ups suggests, and the second set is where nearly all the disagreement on this board comes from.

Last edited: Nov 23, 2025 at 9:52 AM
26 24denise_HTX, raj_cambridge, ingrid_STO and 23 others
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Dr.EndoEP
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Nov 23, 2025 at 2:37 PM#27
NurseKim_ATL said:
The useful move here is to separate what is established from what is widely repeated.

Mine went the same way, slower.

27 0james_edin, FranDenver, Dr.BariatricHTX and 24 others
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DebRD_ATL
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Nov 24, 2025 at 12:22 AM#28
NurseKim_ATL said:
The useful move here is to separate what is established from what is widely repeated.

Coming at NurseKim_ATL’s question from a different direction. Take it one variable at a time. Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent argument can untangle them after the fact.

28 1SleepDoc_PDX, RegAffairsDC, BiostatsBrad and 25 others
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PeptideChemSF
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Nov 24, 2025 at 10:07 AM#29

Adding the numbers, since they settle part of this. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.

Last edited: Nov 24, 2025 at 2:07 PM
29 2ricardo_MIA, BrianDallas92, labquiet_amy and 26 others
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HealthEcon_DC
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Nov 24, 2025 at 7:52 PM#30

Reporting back.

Resolved, and the thing that resolved it was the least interesting suggestion in the thread. Writing that down for the next person who wants the interesting answer.

Last edited: Nov 24, 2025 at 9:52 PM
1 24TrialTracker_MD
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