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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCOA & Analytical TestingHas anyone dealt with moisture content analysis for lyophilized peptides? Page 6

Has anyone dealt with moisture content analysis for lyophilized peptides?

zoe_NC Mon, Oct 20, 2025 at 10:26 AM 31 replies 1,698 viewsPage 6 of 7
Dr.EndoEP
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Jan 9, 2026 at 6:05 AM#26

Adding the clinical framing, because it changes how the question reads. Worth answering the question that was asked rather than the one behind it. The narrow version usually has an answer; the broad version usually does not, and answering the broad one is how a thread stops being useful.

34 9NicoleRaleigh, james_edin, FranDenver and 31 others
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AmyNC_wife
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Jan 20, 2026 at 2:12 AM#27
Dr.EndoEP said:
Worth answering the question that was asked rather than the one behind it.

This is my experience too, for whatever a second data point is worth. Posting only so the count is not one.

33 8julia.endo, JessicaM_2024, TomFromTexas and 30 others
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adam_van
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Jan 30, 2026 at 10:25 PM#28
Dr.EndoEP said:
Worth answering the question that was asked rather than the one behind it.

Coming at Dr.EndoEP’s question from a different direction. It helps to ask what evidence would change your mind before you look at any. If nothing would, the discussion is not about evidence, and it is better to say so early than to spend nine posts discovering it.

32 7LindaRN_retired, tommy_boulder, hyun_seoul and 29 others
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dan_philly
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Feb 10, 2026 at 6:44 PM#29

Adding the numbers, since they settle part of this. For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine. Half the figures circulating in this community trace back to a secondary summary that dropped a qualifier.

Last edited: Feb 10, 2026 at 9:44 PM
31 6Dr.CardioMD, EndoResFellow, PharmacoVig_BOS and 28 others
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zoe_NC
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Charlotte, NC
Feb 21, 2026 at 3:09 PM#30

OP back with an update, since a thread like this is useless without one.

Update: the thing I was blaming turned out not to be the cause. Leaving the original post as written rather than editing it, so the mistake stays visible for whoever searches this next.

9 9mike_mealprep, NicoleRaleigh, james_edin and 6 others
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