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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCOA & Analytical TestingHas anyone dealt with are all coas created equal? mine looks different from others i see? Page 5

Has anyone dealt with are all coas created equal? mine looks different from others i see?

DebRD_ATL Sat, Aug 16, 2025 at 3:55 PM 42 replies 1,906 viewsPage 5 of 9
andrew_nyc
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Apr 2024
New York, NY
Sep 13, 2025 at 8:11 PM#21

A narrower follow-up, since the general answer is now clear:

How would you tell the difference between that and the alternative explanation?

Last edited: Sep 14, 2025 at 1:11 AM
8 6Dr.KarenChen, Dr.NateNeph, PharmD_Rodriguez and 5 others
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jason_paloalto
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Nov 2024
Palo Alto, CA
Sep 24, 2025 at 3:30 AM#22
traveltech_sara said:
My HPLC chromatogram analysis for certificates of analysis — I sent my batch to Janoshik and here's what the results showed: Main peak retention time:…

Community-verified vendors for certificates of analysis: I maintain a spreadsheet of Janoshik-verified test results submitted by community members. Across 49 submitted tests:

  • 78% tested at ≥98% purity
  • 15% tested at 95-98% purity
  • 7% tested at <95% purity (concerning)

The vendors with consistently high purity results are listed in the Vendor Directory. We update monthly based on new community submissions.

9 7Dr.PathRoch, mona_PHX, andrew_nyc and 6 others
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pam_columbus
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Aug 2024
Columbus, OH
Oct 4, 2025 at 10:43 AM#23
traveltech_sara said:
My HPLC chromatogram analysis for certificates of analysis — I sent my batch to Janoshik and here's what the results showed: Main peak retention time:…

Agreed, and the size of the effect matters as much as its existence. Something real and small gets treated here as though it were real and decisive.

I would rather be corrected than agreed with, if it comes to it.

Last edited: Oct 4, 2025 at 4:43 PM
10 8Dr.LipidDallas, alex_tucson, kevin_tulsa and 7 others
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lisa_labSD
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Oct 2024
San Diego, CA
Oct 14, 2025 at 5:50 PM#24
traveltech_sara said:
My HPLC chromatogram analysis for certificates of analysis — I sent my batch to Janoshik and here's what the results showed: Main peak retention time:…

That reframing is the part I needed. Taking it to my next appointment.

11 9lori_vegas, Dr.PulmRoch, maya_sedona and 8 others
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SarahChen_PharmD
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Dec 2023
San Diego, CA
Oct 25, 2025 at 12:50 AM#25

Adding the clinical framing, because it changes how the question reads. The distinction that resolves most of these threads is between what is true on average and what is true for one person. Both are real; they answer different questions and get quoted as if they were the same one.

Last edited: Oct 25, 2025 at 3:50 AM
12 10robert_kc, dan_philly, MeganSA_TX and 9 others
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