Dr.ObesityMed said:The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.
Thank you — that is the clearest version of this I have read, and I have read a lot of them.
Clinical perspective, offered as context rather than as advice. It is worth asking what the claim would look like if it were false. If nothing would look different, it is not a claim about the world and no amount of discussion will settle it.
Dr.Martinez said:It helps to ask what evidence would change your mind before you look at any.
This is where I part company with the consensus forming above. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.
Ask again with the specifics and you will get a better answer than this one.
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View ResultsThe figures, for anyone assembling their own picture. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.
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