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ForumsSide Effects & ManagementPancreatitis risk assessment — need advice

Pancreatitis risk assessment — need advice

nick_newbie Thu, May 30, 2024 at 12:20 AM 63 replies 3,076 viewsPage 1 of 13
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nick_newbie
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Virginia
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May 30, 2024 at 12:20 AM#1

I had a scare that turned out not to be pancreatitis, and the useful thing I took from it was how specific the presentation actually is.

The narrow version of the question is what the pooled safety data actually shows for this class, as opposed to what the label warning implies.

Tell me what I have not thought of.

44 14robert_kc, dan_philly, MeganSA_TX and 41 others
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Dr.NutriCornell
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Ithaca, NY
May 30, 2024 at 12:33 AM#2
nick_newbie said:
I had a scare that turned out not to be pancreatitis, and the useful thing I took from it was how specific the presentation actually is.

Lipase monitoring while on pancreatitis risk: my doctor checks lipase every 3 months given the theoretical pancreatitis risk. All readings have been normal:

  • Baseline: 35 U/L
  • Month 3: 30 U/L
  • Month 6: 28 U/L
  • Month 9: 32 U/L

Normal range is 0-160 U/L. While clinical pancreatitis is rare (<0.5%), I find peace of mind in regular monitoring. Worth asking your doctor about if you're on a GLP-1 long-term.

43 13Dr.SleepRoch, laura_annarbor, JenMemphis and 40 others
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laura_annarbor
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Dec 2024
Ann Arbor, MI
May 30, 2024 at 12:46 AM#3
Dr.NutriCornell said:
Lipase monitoring while on pancreatitis risk: my doctor checks lipase every 3 months given the theoretical pancreatitis risk.

Pancreatitis scare with pancreatitis risk: had severe upper abdominal pain radiating to my back at week 11. Went to the ER — they checked lipase and amylase, both normal. Turned out to be a gallstone.

But I'm glad I went. The risk of pancreatitis, while small (<0.5%), is real. Don't try to tough out severe abdominal pain on a GLP-1 agonist. Get checked.

42 12Dr.SleepRoch, laura_annarbor, JenMemphis and 39 others
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LeilaHI
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Jan 2025
Honolulu, HI
May 30, 2024 at 12:59 AM#4
nick_newbie said:
I had a scare that turned out not to be pancreatitis, and the useful thing I took from it was how specific the presentation actually is.

This matches mine closely enough to be worth saying so out loud. Nothing to add that would improve it.

41 11LondonLisa, mike_nyc, VendorMark and 38 others
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roxy_nash
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Dec 2024
Nashville, TN
May 30, 2024 at 2:09 AM#5

Clinical perspective, offered as context rather than as advice. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

Last edited: May 30, 2024 at 8:09 AM
40 10kim_atl_prep, sarah_TO, wendy_avl and 37 others
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