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Evidence-based GLP-1 & peptide discussion since 2023
ForumsProgress & Lab ResultsMarathon PR after 80 lbs weight loss — anyone have experience? Page 3

Marathon PR after 80 lbs weight loss — anyone have experience?

Dr.LipidDallas Mon, Jul 22, 2024 at 10:32 PM 59 replies 2,635 viewsPage 3 of 12
BethLabQueen
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Jul 24, 2024 at 12:51 PM#11
BariatricNurseD said:
The distinction that resolves most of these threads is between what is true on average and what is true for one person.

That is right, and it stops being right at the edges. The general case is well behaved; the interesting cases in this thread are all at the boundary where the general case breaks.

32 5maya_sedona, stefan_berlin, Dr.EM_Chicago and 29 others
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lisa_labSD
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Jul 24, 2024 at 10:14 PM#12
Dr.AddMedPHL said:
Weight is a noisy signal — daily variation of one to two kilograms from glycogen, sodium and gut contents — so a fortnight of flat readings is well…

That reframing is the part I needed. Adding it to my notes with a link back to this thread.

33 6maya_sedona, stefan_berlin, Dr.EM_Chicago and 30 others
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Dr.RheumBOS
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Jul 25, 2024 at 7:37 AM#13
BariatricNurseD said:
The distinction that resolves most of these threads is between what is true on average and what is true for one person.

Pushing back on BariatricNurseD here. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.

34 7cory_ATX, lori_vegas, Dr.PulmRoch and 31 others
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FDA_TrackerJim
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Jul 25, 2024 at 5:00 PM#14

Adding the numbers, since they settle part of this. If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way. Most of the apparent contradictions in these threads dissolve at that step.

35 8Dr.LeslieOBGYN, MikeNYC_runner and 32 others
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Admin
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Jul 26, 2024 at 2:22 AM#15

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. Report rather than reply if it drifts again.

36 9PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 33 others
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