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ForumsCOA & Analytical TestingMass spectrometry for peptide identity verification — March 2026 Page 6

Mass spectrometry for peptide identity verification — March 2026

JakeBK_lifts Thu, Oct 31, 2024 at 6:08 AM 37 replies 2,134 viewsPage 6 of 8
WendyG_ATL
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Nov 20, 2024 at 7:21 PM#26
sophie_paris said:
If two explanations both fit, the useful question is which one predicts something the other does not.

Can confirm. Same sequence, different timescale. Nothing to add that would improve it.

Last edited: Nov 20, 2024 at 8:21 PM
13 11Dr.SurgeonPGH, rachel_ABQ, traveltech_sara and 10 others
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MarkLI_maint
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Nov 22, 2024 at 2:30 PM#27
sophie_paris said:
If two explanations both fit, the useful question is which one predicts something the other does not.

There is a second half to this that has not been said yet. Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third retelling.

14 12TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 11 others
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BethLabQueen
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Nov 24, 2024 at 9:38 AM#28

Adding the numbers, since they settle part of this. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.

15 13lori_vegas, Dr.PulmRoch, maya_sedona and 12 others
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MASHdoc_SA
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Nov 26, 2024 at 4:45 AM#29

Following on from sophie_paris — and this may be the naive question:

What did you change at the same time, and can you separate the two now?

16 14LabKate, kate.chem, DataDave and 13 others
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JakeBK_lifts
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Nov 27, 2024 at 11:51 PM#30

Closing the loop on my own question.

Follow-up — I put something in the gap where food used to be rather than waiting for the gap to close on its own. That was the part nobody told me.

38 11DataDave, Dr.GutHealth, amsterdam_pete and 35 others
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