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ForumsCOA & Analytical TestingEndotoxin testing methods — what worked for you? Page 7

Endotoxin testing methods — what worked for you?

kevin_tulsa Sat, Oct 19, 2024 at 2:46 AM 37 replies 2,040 viewsPage 7 of 8
PharmHunterJen
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Oct 24, 2024 at 10:18 PM#31

Adding the clinical framing, because it changes how the question reads. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.

Ask again with the specifics and you will get a better answer than this one.

23 21Dr.LipidDallas, alex_tucson, kevin_tulsa and 20 others
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PeptideChemSF
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Oct 25, 2024 at 7:08 AM#32
PharmHunterJen said:
The mechanism and the magnitude are separate questions.

Mine went the same way, slower.

24 22dave_SLC, FDA_TrackerJim, ricardo_MIA and 21 others
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wendy_avl
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Oct 25, 2024 at 3:58 PM#33
PharmHunterJen said:
The mechanism and the magnitude are separate questions.

Adding the part of the answer the thread has not reached. The useful move here is to separate what is established from what is widely repeated. Those two sets overlap less than the confident tone of most write-ups suggests, and the second set is where nearly all the disagreement on this board comes from.

25 23TomTeleRx, DoseLogDan, SleepFixSam and 22 others
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Dr.NateNeph
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Oct 26, 2024 at 12:48 AM#34

The figures, for anyone assembling their own picture. If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way. Most of the apparent contradictions in these threads dissolve at that step.

Last edited: Oct 26, 2024 at 2:48 AM
26 24B12Beth, RickReta_CO, PharmHunterJen and 23 others
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LipidDoc_ATL
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Oct 26, 2024 at 9:37 AM#35

A narrower follow-up, since the general answer is now clear:

Was that from a primary source or from a summary of one?

Last edited: Oct 26, 2024 at 2:37 PM
27 0KristenIndy, MarkLI_maint, Dr.PeteFamMed and 24 others
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