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Evidence-based GLP-1 & peptide discussion since 2023
ForumsDosing & ProtocolsMy doctor says stay on 1mg but I feel like I need more — anyone have experience? Page 7

My doctor says stay on 1mg but I feel like I need more — anyone have experience?

AussieAnna Thu, Apr 4, 2024 at 3:35 PM 42 replies 2,345 viewsPage 7 of 9
pat_auckland
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Apr 10, 2024 at 11:21 AM#31
EndoResFellow said:
The mechanism and the magnitude are separate questions.

Adding the part of the answer the thread has not reached. Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third retelling.

Ask again with the specifics and you will get a better answer than this one.

31 4NurseAsh_DET, BenResearch_OR, MikeKY_noInsulin and 28 others
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DataDave
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Apr 10, 2024 at 5:34 PM#32

One concrete data point for the thread. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.

32 5mike_nyc, VendorMark, COA_Karl and 29 others
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pete_nash
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Apr 10, 2024 at 11:47 PM#33

Following on from EndoResFellow — and this may be the naive question:

Was that from a primary source or from a summary of one?

33 6mike_mod, SarahChen_PharmD, sarah.morrison and 30 others
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FitDadDave
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Apr 11, 2024 at 6:00 AM#34
DataDave said:
Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…

Pushing back on DataDave here. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.

Last edited: Apr 11, 2024 at 9:00 AM
34 7wendy_avl, jason_paloalto, Dr.LeslieOBGYN and 31 others
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Dr.Martinez
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Apr 11, 2024 at 12:12 PM#35
DataDave said:
Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…

No disagreement, though it depends on where somebody is starting from, and this thread has been assuming a starting point nobody stated.

35 8adam_van, Dr.SurgeonPGH, rachel_ABQ and 32 others
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