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Evidence-based GLP-1 & peptide discussion since 2023
ForumsMetabolic Health & DiabetesGLP-1 and gluconeogenesis — what worked for you? Page 3

GLP-1 and gluconeogenesis — what worked for you?

matt_MKE Mon, Oct 20, 2025 at 10:35 AM 50 replies 1,666 viewsPage 3 of 10
LipidDoc_ATL
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Oct 23, 2025 at 12:40 AM#11
PharmD_Rodriguez said:
Fasting insulin is the lab my functional medicine doctor cares about most for glycaemic control: it's a much earlier marker of metabolic dysfunction…

That holds where the measurement is reliable. Where it is noisy — and a lot of what gets tracked here is noisy — the same reasoning produces confident nonsense.

I would rather be corrected than agreed with, if it comes to it.

29 2rachel_ABQ, traveltech_sara, AttorneyGrant and 26 others
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jason_sac26
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Jan 2026
Sacramento, CA
Oct 24, 2025 at 2:41 PM#12
rick_sfbay said:
Complete metabolic panel trending on glycaemic control — sharing because comprehensive data helps everyone: Test Baseline Month 3 Month 6 Month 12…

This answered a question I did not know how to ask. Sending this to two other people who asked me the same thing last week.

30 3Dr.EM_Chicago, pete_RVA, CarlaRPh_TPA and 27 others
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mia_MS2
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Ann Arbor, MI
Oct 26, 2025 at 4:40 AM#13
PharmD_Rodriguez said:
Fasting insulin is the lab my functional medicine doctor cares about most for glycaemic control: it's a much earlier marker of metabolic dysfunction…

Pushing back on PharmD_Rodriguez here. Pushing back on the consensus forming here. Consistency is not the same as correctness, and a board that agrees with itself quickly is usually agreeing with the first person who sounded certain.

31 4dave_SLC, FDA_TrackerJim, ricardo_MIA and 28 others
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LabKate
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Oregon
Oct 27, 2025 at 6:40 PM#14

The figures, for anyone assembling their own picture. Worth stating the units and the reference range whenever you post a number here. A large fraction of the apparent disagreement in these threads is two people using different units and both being right.

32 5emily_PDX, Dr.SleepRoch, laura_annarbor and 29 others
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Admin
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Oct 29, 2025 at 8:38 AM#15

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source. Report rather than reply if it drifts again.

33 6PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 30 others
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