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ForumsMetabolic Health & DiabetesGLP-1 and gluconeogenesis — what worked for you? Page 7

GLP-1 and gluconeogenesis — what worked for you?

matt_MKE Mon, Oct 20, 2025 at 10:35 AM 50 replies 1,666 viewsPage 7 of 10
SarahChen_PharmD
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Jan 14, 2026 at 5:42 PM#31

Following on from traveltech_sara — and this may be the naive question:

What did you change at the same time, and can you separate the two now?

Last edited: Jan 14, 2026 at 8:42 PM
41 14Dr.ObesityLA, NurseKim_ATL, paul_denver and 38 others
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SleepFixSam
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Jan 21, 2026 at 11:04 AM#32
matt_MKE said:
I changed one thing, left everything else alone, and waited the full interval before looking.

I do not accept the framing. The question has been narrowed to the version that has a tidy answer, and the part that was dropped is the part the OP actually asked about.

42 15ingrid_STO, pete_nash, hank_denver and 39 others
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NurseLeah_Nash
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Jan 28, 2026 at 4:23 AM#33
matt_MKE said:
I changed one thing, left everything else alone, and waited the full interval before looking.

No disagreement, though it depends on where somebody is starting from, and this thread has been assuming a starting point nobody stated.

Last edited: Jan 28, 2026 at 5:23 AM
43 16PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 40 others
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sarah_TO
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Feb 3, 2026 at 9:39 PM#34
matt_MKE said:
I changed one thing, left everything else alone, and waited the full interval before looking.

Saving this. It is the first explanation that did not require me to already understand it.

Last edited: Feb 4, 2026 at 1:39 AM
44 17carl_compliance, DanielChem_CHI, marco_milano and 41 others
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Dr.CardioMD
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Feb 10, 2026 at 2:51 PM#35

From the other side of the consultation, briefly. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.

45 18josh_phd_bmore, roxy_nash, tony_orlando and 42 others
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