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ForumsMetabolic Health & DiabetesSURPASS-CVOT: tirzepatide cardiovascular outcomes trial design — looking for input Page 4

SURPASS-CVOT: tirzepatide cardiovascular outcomes trial design — looking for input

Admin Sat, Jul 12, 2025 at 7:09 AM 40 replies 1,896 viewsPage 4 of 8
Dr.PainCLE
Senior Member
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Cleveland, OH
Jul 30, 2025 at 11:08 PM#16

Adding the clinical framing, because it changes how the question reads. The distinction that resolves most of these threads is between what is true on average and what is true for one person. Both are real; they answer different questions and get quoted as if they were the same one.

Correct me if the detail matters more than I have assumed.

Last edited: Jul 31, 2025 at 2:08 AM
26 24Dr.PathRoch, mona_PHX, andrew_nyc and 23 others
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carlos_SATX
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Oct 2024
San Antonio, TX
Aug 2, 2025 at 10:03 PM#17
TrialTracker_MD said:
Worth stating the units and the reference range whenever you post a number here.

No disagreement, though it depends on where somebody is starting from, and this thread has been assuming a starting point nobody stated.

Worth separating that from cardiovascular outcomes, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.

27 0FranDenver, Dr.BariatricHTX, LindaRN_retired and 24 others
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tony_orlando
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Nov 2024
Orlando, FL
Aug 5, 2025 at 8:57 PM#18
TrialTracker_MD said:
Worth stating the units and the reference range whenever you post a number here.

This is exactly what I could not find anywhere else.

28 1ZaraB_AL, JakeSmashed95, NauseaFreeNow and 25 others
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LindaRN_retired
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Dec 2024
Sarasota, FL
Aug 8, 2025 at 7:49 PM#19

Clinical perspective, offered as context rather than as advice. Start from the measurement rather than the conclusion. Almost every disagreement here turns out to be two people measuring different things and comparing the numbers anyway.

Last edited: Aug 8, 2025 at 10:49 PM
29 2LondonLisa, mike_nyc, VendorMark and 26 others
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andrew_nyc
Member
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Apr 2024
New York, NY
Aug 11, 2025 at 6:40 PM#20

Moderator note: a post naming a supplier has been edited. Discuss suppliers in the review sections, not here. Thread quality here is what the rules are for. Keep it up.

Last edited: Aug 11, 2025 at 11:40 PM
1 24JessicaM_2024
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