🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsMetabolic Health & DiabetesSURPASS-CVOT: tirzepatide cardiovascular outcomes trial design — looking for input Page 7

SURPASS-CVOT: tirzepatide cardiovascular outcomes trial design — looking for input

Admin Sat, Jul 12, 2025 at 7:09 AM 40 replies 1,896 viewsPage 7 of 8
hans_munich
Member
534
2,345
Jul 2024
Munich, DE
Dec 28, 2025 at 1:35 PM#31

Following on from Dr.ReproEndo — and this may be the naive question:

Did your prescriber agree with that reading, and if not what was their objection?

33 6kevin_tulsa, Dr.PainCLE, mike_mealprep and 30 others
Reply Quote Save Share Report
mike_nyc
VIP Member
5,678
21,345
Nov 2023
New York
Online
Jan 11, 2026 at 12:27 AM#32
Admin said:
Update, and it is the boring outcome: nothing was wrong.

Pushing back on Admin here. I would resist the confidence. Half of what this board was certain about two years ago has since been quietly dropped, and nobody went back to correct the threads.

34 7stefan_berlin, Dr.EM_Chicago, pete_RVA and 31 others
Reply Quote Save Share Report
Dr.NephBHM_UK
Member
456
2,123
Jun 2024
Birmingham, UK
Jan 24, 2026 at 11:12 AM#33
Admin said:
Update, and it is the boring outcome: nothing was wrong.

Agreed on the substance. I would put less weight on the timescale, because two months of anything is not enough to distinguish a trend from a wobble.

35 8PharmacoVig_BOS, SurmountFan_IN, PeptideChemSF and 32 others
Reply Quote Save Share Report

Sigma-Aldrich — Research-Grade Standards

Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.

Shop Reference Standards
Dr.NutriCornell
Senior Member
1,345
6,234
Mar 2024
Ithaca, NY
Feb 6, 2026 at 9:49 PM#34
Admin said:
Update, and it is the boring outcome: nothing was wrong.

Thank you for spelling out the reasoning rather than just the conclusion.

Last edited: Feb 6, 2026 at 11:49 PM
36 9JenMemphis, pat_auckland, Dr.GastroMayo and 33 others
Reply Quote Save Share Report
ingrid_STO
Member
345
1,456
Jul 2024
Stockholm, SE
Feb 20, 2026 at 8:18 AM#35

Clinical perspective, offered as context rather than as advice. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.

Last edited: Feb 20, 2026 at 11:18 AM
37 10WendyG_ATL, SaraMom3, Dr.MetabolicMD and 34 others
Reply Quote Save Share Report

Similar Threads

SUSTAIN-6 to SELECT — the cardiovascular evidence timeline14 replies
GLP-1 and insulin resistance — HOMA-IR improvement data17 replies
Metabolic syndrome reversal criteria — how GLP-1 addresses all 55 replies
A1C target achievement rates — sema vs tirz comparison8 replies
SURPASS-CVOT: tirzepatide cardiovascular outcomes trial design3 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register