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Evidence-based GLP-1 & peptide discussion since 2023
ForumsMetabolic Health & DiabetesGLP-1 and beta-cell preservation — looking for input Page 3

GLP-1 and beta-cell preservation — looking for input

steph_laguna Thu, Oct 31, 2024 at 6:17 AM 52 replies 2,916 viewsPage 3 of 11
kate.chem
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Nov 1, 2024 at 4:32 AM#11
DebRD_ATL said:
PCOS success story with glycaemic control: as someone with polycystic ovary syndrome, this medication has been transformative beyond weight loss.

Correct, and worth adding that it is reversible. Nothing being described here is a one-way door, which changes how cautious it is reasonable to be.

Last edited: Nov 1, 2024 at 7:32 AM
14 14steve_okc, dave_SLC, FDA_TrackerJim and 11 others
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MASHdoc_SA
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Nov 1, 2024 at 8:31 PM#12
NurseAsh_DET said:
Patient selection optimization for glycaemic control: emerging predictive biomarkers for GLP-1 agonist response include: Biomarker Association…

Saving this. It is the first explanation that did not require me to already understand it. Printing the relevant bit and taking it with me.

Last edited: Nov 1, 2024 at 11:31 PM
13 13TrialTracker_MD, JennaRN, LabKate and 10 others
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LarryQC_SD
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Nov 2, 2024 at 12:30 PM#13
DebRD_ATL said:
PCOS success story with glycaemic control: as someone with polycystic ovary syndrome, this medication has been transformative beyond weight loss.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. The objection nobody has made: this only works if the measurement is doing what we assume it is doing, and that assumption has not been tested here.

12 12TinaHashiRN, robert_kc, dan_philly and 9 others
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dan_philly
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Nov 3, 2024 at 4:28 AM#14

One concrete data point for the thread. One practical note: write down what you did and when, before you need it. Reconstructing a timeline from memory three months later is how people end up unable to answer the one question that would have resolved it.

Last edited: Nov 3, 2024 at 7:28 AM
11 11Dr.CardioMD, EndoResFellow, PharmacoVig_BOS and 8 others
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mike_mod
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Nov 3, 2024 at 8:26 PM#15

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. No action needed from anybody.

10 10PurityPaulOR, MaxMetOK, MounjBrad and 7 others
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