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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPsychological & BehavioralGoal weight anxiety — fear of what happens when you arrive

Goal weight anxiety — fear of what happens when you arrive

mel_PDX Mon, May 11, 2026 at 9:21 PM 21 replies 770 viewsPage 1 of 5
mel_PDX
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Dec 2024
Portland, OR
May 11, 2026 at 9:21 PM#1

My mood has been flatter since about month four and I genuinely cannot work out whether that is the drug, the deficit, or the fact that I no longer have my main coping mechanism.

What would genuinely help is knowing how people separated a drug effect from the ordinary consequences of a large deficit and disrupted sleep, because I cannot.

I have searched first, so if this is covered somewhere point me at it and I will read it.

35 5Dr.NateNeph, PharmD_Rodriguez, julia.endo and 32 others
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DebRD_ATL
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Feb 2024
Atlanta, GA
May 11, 2026 at 9:51 PM#2
mel_PDX said:
My mood has been flatter since about month four and I genuinely cannot work out whether that is the drug, the deficit, or the fact that I no longer…

Recovering from an eating disorder and using mental health: this is a complex situation and I want to be transparent about it.

I have a history of binge eating disorder. My psychiatrist, therapist, and prescribing doctor all collaborate on my care. The GLP-1 agonist has actually been therapeutic — it removes the biological urgency of binge impulses without relying on restriction.

This is NOT appropriate for all ED patients. Anorexia, bulimia, and restrictive EDs require different approaches. But for BED specifically, the evidence and my personal experience are positive. Always involve your mental health team.

Last edited: May 12, 2026 at 1:51 AM
34 4RegAffairsDC, BiostatsBrad, PeptideSynthNJ and 31 others
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CryptoCarl
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May 2024
Arizona
May 11, 2026 at 10:21 PM#3
DebRD_ATL said:
Recovering from an eating disorder and using mental health: this is a complex situation and I want to be transparent about it.

Anxiety increase on mental health: counterintuitive, but losing weight rapidly triggered anxiety for me. Change — even positive change — is stressful. I was anxious about people treating me differently.

This is more common than people admit. A therapist who specializes in weight management has been invaluable. Don't neglect the mental health side of this journey.

Last edited: May 12, 2026 at 2:21 AM
33 3AussieAnna, BethLabQueen, ChrisMacros and 30 others
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gary_naperville
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Oct 2024
Naperville, IL
May 11, 2026 at 10:51 PM#4
mel_PDX said:
My mood has been flatter since about month four and I genuinely cannot work out whether that is the drug, the deficit, or the fact that I no longer…

Second this. Posting only so the count is not one.

32 2PharmHunterJen, TomTeleRx, DoseLogDan and 29 others
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traveltech_sara
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Jan 2025
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May 12, 2026 at 1:34 AM#5

Adding the clinical framing, because it changes how the question reads.

mel_PDX said:
...mental health should only be used alongside therapy...

I'd say therapy should be AVAILABLE to all GLP-1 patients, but requiring it as a precondition for treatment would create an access barrier.

Not everyone can afford therapy. Not everyone needs it. Some people do just fine with medication + lifestyle changes. But for those with emotional eating, body image issues, or disordered eating history, therapy is extremely valuable.

My recommendation: make mental health screening part of the initial assessment, offer therapy as a recommended adjunct, but don't gatekeep medication access behind it.

31 1BenResearch_OR, MikeKY_noInsulin, Dr.RaviCardio and 28 others
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