From the other side of the consultation, briefly. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.
TrialTracker_MD said:If two explanations both fit, the useful question is which one predicts something the other does not.
Adding a me-too, because a thread of one person's experience is not much use. Nothing to add that would improve it.
TrialTracker_MD said:If two explanations both fit, the useful question is which one predicts something the other does not.
Coming at TrialTracker_MD’s question from a different direction. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.
Sigma-Aldrich — Research-Grade Standards
Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.
Shop Reference StandardsOne concrete data point for the thread. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.
Reporting back.
Following up because I said I would. I changed one thing, left everything else alone, and waited the full interval before looking. It resolved, and I cannot prove which half of that did it.