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Evidence-based GLP-1 & peptide discussion since 2023
ForumsOral GLP-1 AgonistsPLEASE just give me a pill already I hate needles so much — looking for input Page 2

PLEASE just give me a pill already I hate needles so much — looking for input

RegAffairsDC Mon, Jun 23, 2025 at 6:04 PM 12 replies 1,406 viewsPage 2 of 3
Dr.PeteFamMed
Senior Member
2,012
9,234
Jan 2024
Minneapolis, MN
Jun 24, 2025 at 5:00 AM#6

The figures, for anyone assembling their own picture. One habit that pays for itself: post the method alongside the number. A figure without its method cannot be checked, and an unchecked figure is how this community accumulates folklore.

9 4hyun_seoul, jim_asheville, matt_MKE and 6 others
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hannah_MT
New Member
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89
Feb 2026
Bozeman, MT
Jun 24, 2025 at 9:19 AM#7

One thing that is still open after Dr.BariatricHTX’s answer:

Whether the fasting requirement is as strict in practice as the label implies, and what people actually see when they get it wrong?

8 3MounjBrad, nick_newbie, DadBodDave and 5 others
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PedsEndoPhilly
Member
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Jun 2024
Philadelphia, PA
Jun 24, 2025 at 1:38 PM#8
Dr.PeteFamMed said:
One habit that pays for itself: post the method alongside the number.

Adding the part of the answer the thread has not reached. The version of this that has an answer is narrower than the version being asked. Narrow it and it becomes tractable; leave it broad and the thread will produce nine confident and incompatible replies.

7 2jason_paloalto, Dr.LeslieOBGYN, MikeNYC_runner and 4 others
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RegAffairsDC
Member
678
3,456
May 2024
Washington, DC
Jun 24, 2025 at 5:57 PM#9

Closing the loop on my own question.

I moved the tablet to the moment I wake up rather than trying to fit it around breakfast, and the difference in the following weeks was obvious. It was a timing problem, not a dose problem.

6 1sean_dublin, hannah_MT, Dr.SportsMedIN and 3 others
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hans_munich
Member
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Jul 2024
Munich, DE
Jun 25, 2025 at 2:40 PM#10
PedsEndoPhilly said:
The version of this that has an answer is narrower than the version being asked.

PedsEndoPhilly has the substance of this right. The condition it depends on is worth stating. Worth adding that the tablet is taken daily, so a missed dose costs far less than a missed weekly injection. That is a genuine advantage nobody lists.

42 15emma_london, tammy_FL, Dr.LipidDallas and 39 others
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