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Evidence-based GLP-1 & peptide discussion since 2023
ForumsOral GLP-1 AgonistsHow far away are we really from an oral option — 12 month update Page 4

How far away are we really from an oral option — 12 month update

HPLC_Greg Wed, Jun 4, 2025 at 7:45 PM 47 replies 2,552 viewsPage 4 of 10
TrialNerd_Beth
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Jun 6, 2025 at 2:27 AM#16

Clinical perspective, offered as context rather than as advice. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

Correct me if the detail matters more than I have assumed.

27 0RickReta_CO, PharmHunterJen, TomTeleRx and 24 others
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hyun_seoul
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Seoul, KR
Jun 6, 2025 at 6:24 AM#17
dan_philly said:
The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…

Thank you for spelling out the reasoning rather than just the conclusion.

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Dr.SleepRoch
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Jun 6, 2025 at 10:21 AM#18

From the other side of the consultation, briefly. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.

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SandraNC_45
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Jun 6, 2025 at 2:18 PM#19
Dr.SleepRoch said:
If two explanations both fit, the useful question is which one predicts something the other does not.

Same experience, arrived at from the opposite direction.

30 3mike_mealprep, NicoleRaleigh, james_edin and 27 others
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mike_mod
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Jun 6, 2025 at 6:15 PM#20

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. Thread quality here is what the rules are for. Keep it up.

2 0PurityPaulOR, MaxMetOK
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