TrialNerd_Beth said:Month 6 update on sleep apnoea: down 48 lbs from my starting weight of 293 lbs.
Adding a me-too, because a thread of one person's experience is not much use. I had assumed I was the exception until I read this.
From the other side of the consultation, briefly. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.
TrialTracker_MD said:If two explanations both fit, the useful question is which one predicts something the other does not.
Same pattern here, and in the same order. The detail I would add is minor and it is already implied above.
Community-driven peptide testing and vendor rating platform. Transparent results. Unbiased analysis. Trusted by thousands.
View ResultsTrialTracker_MD said:If two explanations both fit, the useful question is which one predicts something the other does not.
Coming at TrialTracker_MD’s question from a different direction. SURMOUNT-1 landed around 20.9% mean weight loss at 15mg over 72 weeks, against roughly 15% for semaglutide 2.4mg in STEP 1. Different trials, different populations, so the comparison is indicative rather than decisive — but SURPASS-2 was a genuine head-to-head and it pointed the same way.
Happy to go further on any of that.
Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. Tagging this one for the weekly digest.