Clinical perspective, offered as context rather than as advice. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.
That is the short version; the long version is somebody else's post.
One thing that is still open after TomTeleRx’s answer:
Was that from a primary source or from a summary of one?
Dr.AddMedPHL said:There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.
This is where I part company with the consensus forming above. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.
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Shop Reference StandardsDr.AddMedPHL said:There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.
That is right, and it stops being right at the edges. The general case is well behaved; the interesting cases in this thread are all at the boundary where the general case breaks.