josh_phd_bmore said:If you are going to change something, change one thing and give it long enough to express itself.
I am going to disagree with the direction of travel here. The thread has converged on the tidiest answer rather than the best-supported one, and those are not the same thing.
josh_phd_bmore said:If you are going to change something, change one thing and give it long enough to express itself.
Correct as far as it goes. The part it does not cover is what to do when the honest answer is "not enough data", which is more often than anyone likes.
Happy to go further on any of that.
josh_phd_bmore said:If you are going to change something, change one thing and give it long enough to express itself.
Genuinely useful, thank you. I had the facts and not the framework. I will report back once I have actually tried it.
Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.
Shop Reference StandardsAdding the clinical framing, because it changes how the question reads. Take it one variable at a time. Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent argument can untangle them after the fact.
I would rather be corrected than agreed with, if it comes to it.
OP back with an update, since a thread like this is useless without one.
Update: the thing I was blaming turned out not to be the cause. Leaving the original post as written rather than editing it, so the mistake stays visible for whoever searches this next.