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ForumsCardiovascular OutcomesLp(a) on GLP-1 agonists — March 2026

Lp(a) on GLP-1 agonists — March 2026

quinn_sf Thu, Apr 16, 2026 at 6:38 PM 19 replies 901 viewsPage 1 of 4
quinn_sf
Member
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Jun 2024
San Francisco, CA
Apr 16, 2026 at 6:38 PM#1

Trying to work out whether my panel improved or merely rearranged itself, because two of the numbers went the wrong way.

What I actually want to know is whether an unchanged LDL-C alongside a large triglyceride fall is a good result or a bad one, because ApoB and LDL-C seem to be telling different stories.

Numbers rather than impressions, if you have them.

39 9tane_welly, Dr.PathRoch, mona_PHX and 36 others
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JessicaH_TX
Senior Member
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13,456
Dec 2023
Houston, TX
Apr 16, 2026 at 6:44 PM#2
quinn_sf said:
Trying to work out whether my panel improved or merely rearranged itself, because two of the numbers went the wrong way.

Tracking labs for the lipid panel — here's the panel I get every 3 months and why:

  • CMP: glucose, electrolytes, kidney function, liver enzymes
  • Lipid panel: total cholesterol, LDL, HDL, triglycerides
  • A1C: 3-month glucose average
  • hsCRP: inflammatory marker
  • CBC: blood counts, anemia screening
  • B12, folate, iron: nutritional deficiency screening
  • TSH, free T4: thyroid monitoring
  • Lipase: pancreatic safety check

Total cost with insurance: about $44 copay. Without insurance, request cash-pay pricing from Quest/Labcorp — usually $179.

38 8sarah_TO, wendy_avl, jason_paloalto and 35 others
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RickReta_CO
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Jan 2025
Colorado
Apr 16, 2026 at 6:50 PM#3
JessicaH_TX said:
Tracking labs for the lipid panel — here's the panel I get every 3 months and why: CMP: glucose, electrolytes, kidney function, liver enzymes Lipid…

Comprehensive lipid panel update relevant to the lipid panel:

MarkerBaseline6 Months12 MonthsReference
Total Cholesterol269204194<200
LDL154119114<100
HDL474861>40
Triglycerides289174104<150
LDL-P17291179979<1000

The triglyceride drop is the most impressive. My cardiologist reduced my statin dose based on these results.

Last edited: Apr 16, 2026 at 11:50 PM
37 7hyun_seoul, jim_asheville, matt_MKE and 34 others
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rick_sfbay
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Jan 2025
San Francisco, CA
Apr 16, 2026 at 6:56 PM#4
quinn_sf said:
Trying to work out whether my panel improved or merely rearranged itself, because two of the numbers went the wrong way.

Mine went the same way, slower.

36 6FranDenver, Dr.BariatricHTX, LindaRN_retired and 33 others
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Dr.KarenChen
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Nov 2023
San Francisco, CA
Apr 16, 2026 at 7:26 PM#5

Clinical perspective, offered as context rather than as advice.

Omega-3 index improvement on the lipid panel: often overlooked but my omega-3 index went from 3.9% to 8.9% over 10 months. I supplemented with 2g EPA+DHA daily.

This matters because omega-3s are anti-inflammatory and cardioprotective, complementing the GLP-1 benefits. Target omega-3 index is >8%. Combined with the triglyceride reduction from the medication, my lipid profile is the best it's been in decades.

Last edited: Apr 17, 2026 at 1:26 AM
35 5sarah_nash92, FitDadDave, RunnerRach and 32 others
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