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ForumsCompounding & FormulationBacteriostatic water sourcing and sterility considerations — my results so far Page 2

Bacteriostatic water sourcing and sterility considerations — my results so far

FranDenver Sat, Oct 4, 2025 at 8:11 PM 7 replies 1,106 viewsPage 2 of 2
Dr.RenalNash
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Oct 4, 2025 at 9:57 PM#6
BenResearch_OR said:
Concentration choice is a precision decision, not a preference.

I am going to disagree with reconstituting low as a general rule. More diluent, more punctures, more in-use days at room temperature, and the stability trade-off is real. Precision is not the only variable being optimised.

23 1wei_SG, cory_ATX, lori_vegas and 20 others
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BethLabQueen
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Oct 4, 2025 at 10:38 PM#7

The figures, for anyone assembling their own picture. Red flags, in rough order of how much they should worry you: no verifiable address, no batch numbers, prices far under market, vendor-commissioned tests only, pressure toward irreversible payment, and shipping with no temperature control.

Last edited: Oct 4, 2025 at 11:38 PM
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PharmacoVig_BOS
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Oct 4, 2025 at 11:19 PM#8
Dr.RenalNash said:
I am going to disagree with reconstituting low as a general rule.

Coming at Dr.RenalNash’s question from a different direction. The useful checklist is about verifiability rather than presentation. Independent test results commissioned by buyers rather than by the seller, consistency across multiple batches over time rather than one flattering report, a physical address and a company registration that resolve, batch and lot numbers on the actual labelling, and a shipping practice that matches what the material needs. Everything a good-looking website provides is cheap to fake; none of the items above are.

Worth separating that from vendor vetting, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.

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pat_auckland
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Oct 5, 2025 at 12:00 AM#9

A narrower follow-up, since the general answer is now clear:

How much material I am losing to dead space, and whether that explains why a 10mg vial gives me nine usable draws rather than ten?

Last edited: Oct 5, 2025 at 4:00 AM
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FranDenver
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Oct 5, 2025 at 3:17 AM#10

OP back with an update, since a thread like this is useless without one.

Follow-up: it was dead space. Switching to a low-dead-space fixed-needle syringe gave me the tenth dose back.

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