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ForumsPublic SquareSemaglutide and gallbladder disease risk — my results so far Page 6

Semaglutide and gallbladder disease risk — my results so far

lisa_labSD Wed, Jun 4, 2025 at 10:48 PM 44 replies 2,339 viewsPage 6 of 9
LipidDoc_ATL
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Sep 9, 2025 at 6:56 AM#26

Adding the clinical framing, because it changes how the question reads. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.

40 13rachel_ABQ, traveltech_sara, AttorneyGrant and 37 others
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alex_tucson
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Sep 22, 2025 at 5:59 AM#27
LipidDoc_ATL said:
If two explanations both fit, the useful question is which one predicts something the other does not.

Same pattern here, and in the same order. Posting only so the count is not one.

Last edited: Sep 22, 2025 at 7:59 AM
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JenPlateau
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Oct 5, 2025 at 4:54 AM#28
LipidDoc_ATL said:
If two explanations both fit, the useful question is which one predicts something the other does not.

Coming at LipidDoc_ATL’s question from a different direction. Steady state is the thing most people miss. The terminal half-life is about a week, so every dose step takes four to five weeks to fully express itself. Judging a step at day ten is judging the ascent, not the plateau, and it is the single commonest reason people escalate before they needed to.

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SleepDoc_PDX
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Oct 18, 2025 at 3:41 AM#29

The figures, for anyone assembling their own picture. Keep the original post as written when you update it, and add the correction underneath. An edited-away mistake is invisible to the next person who makes it.

Worth separating that from semaglutide, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.

43 16sophie_paris, mel_PDX, Dr.AddMedPHL and 40 others
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lisa_labSD
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Oct 31, 2025 at 2:22 AM#30

OP back with an update, since a thread like this is useless without one.

Update. I did go to 2.4mg in the end, and the honest report is that it bought me less than the step before it and cost me two bad weeks. Worth knowing rather than worth repeating.

15 13cory_ATX, lori_vegas, Dr.PulmRoch and 12 others
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