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Evidence-based GLP-1 & peptide discussion since 2023
ForumsLab Results & BiomarkersComplete metabolic panel guide — what each value means during GLP-1 therapy Page 3

Complete metabolic panel guide — what each value means during GLP-1 therapy

JennaRN Mon, Feb 19, 2024 at 5:20 PM 57 replies 43,511 viewsPage 3 of 12
KetoKyle
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Feb 24, 2024 at 2:10 PM#11
paige_pharma said:
Quarterly for the first year is convention rather than evidence, and it is defensible for a simple reason: it is roughly the interval over which HbA1c…

Thank you for spelling out the reasoning rather than just the conclusion.

9 9laura_annarbor, JenMemphis, pat_auckland and 6 others
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anders_CPH
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Feb 24, 2024 at 6:50 PM#12

Clinical perspective, offered as context rather than as advice.

Shot day Thursday report relevant to baseline bloodwork:

Week 32. Currently on 10mg. Down 58 lbs from starting weight of 270 lbs.

This week's observations: Energy levels excellent, zero nausea.

Labs due next week — looking forward to seeing the metabolic panel. I'll post results in the Lab Results section when they come in.

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DebRD_ATL
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Feb 24, 2024 at 11:30 PM#13
Dr.NutriCornell said:
The single most useful discipline is bringing the whole panel to a clinician rather than one flagged value.

This is where I part company with the consensus forming above. I would be careful about how confidently the flatness reports get attributed. Rapid weight loss, a large deficit and disrupted sleep produce low mood on their own, and separating that from a drug effect is genuinely hard.

Last edited: Feb 25, 2024 at 3:30 AM
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LabKate
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Feb 25, 2024 at 4:09 AM#14
JennaRN said:
Complete metabolic panel guide — what each value means during GLP-1 therapy Posting this as an important update for the lab results & biomarkers…

PSA: get baseline labs BEFORE starting baseline bloodwork therapy. You need a "before" picture to measure progress. My recommended pre-treatment panel:

  1. CMP + A1C + fasting insulin
  2. Complete lipid panel with particle count if possible
  3. hsCRP, ferritin, B12, vitamin D
  4. Thyroid panel (TSH + free T4)
  5. CBC with differential
  6. Liver panel (ALT, AST, GGT)
  7. DEXA scan or body composition

Total cost at Quest without insurance: ~$200. Worth every penny for the data.

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mike_mod
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Feb 25, 2024 at 8:48 AM#15

Moderator note: a couple of off-topic posts removed.

Last edited: Feb 25, 2024 at 10:48 AM
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