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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCardiovascular OutcomesMy blood pressure normalization journey — July 2024 Page 3

My blood pressure normalization journey — July 2024

JessicaH_TX Sat, Aug 16, 2025 at 1:11 PM 25 replies 1,700 viewsPage 3 of 5
Dr.NutriCornell
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Aug 21, 2025 at 4:49 AM#11
Dr.PainCLE said:
I'm 48 years old and want to share my perspective on cardiovascular risk as an older member of this community.

6 month update on cardiovascular risk: down 50 lbs, off blood pressure meds, A1C normalized. Genuinely life-changing.

8 8emily_PDX, Dr.SleepRoch, laura_annarbor and 5 others
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newstart_MO
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Aug 23, 2025 at 5:16 PM#12
jason_paloalto said:
Dr.SleepRoch said: ...we don't know the long-term effects of cardiovascular risk...

Thank you — that is the clearest version of this I have read, and I have read a lot of them. Sending this to two other people who asked me the same thing last week.

Last edited: Aug 23, 2025 at 11:16 PM
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marco_milano
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Aug 26, 2025 at 5:44 AM#13
Dr.PainCLE said:
I'm 48 years old and want to share my perspective on cardiovascular risk as an older member of this community.

Dizziness and cardiovascular risk: I was lightheaded for the first 3 weeks. Root cause was a combination of reduced caloric intake and mild dehydration.

Fix: minimum 80-100oz water daily, don't skip meals even if you're not hungry (eat small protein-rich snacks), and stand up slowly from sitting/lying positions. Also check your blood pressure — GLP-1-induced weight loss can make BP meds too strong, requiring dose reduction.

6 6Dr.LipidDallas, alex_tucson, kevin_tulsa and 3 others
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BiostatsBrad
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Aug 28, 2025 at 6:14 PM#14
JessicaH_TX said:
Prescribed on cardiovascular grounds rather than for weight, and almost everything written for patients assumes the opposite.

Positive "side effect" of cardiovascular risk: my blood pressure dropped so much that I'm now off losartan entirely! My cardiologist is thrilled.

If you're on BP meds and losing weight on a GLP-1, monitor your BP at home regularly. Hypotension symptoms (dizziness, lightheadedness when standing) mean your BP meds may need reduction. Don't wait for your next scheduled appointment — call your doctor.

Last edited: Aug 28, 2025 at 7:14 PM
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Admin
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Aug 31, 2025 at 6:45 AM#15

Moderator note: the sourcing question belongs in the vendor section and has been split out. Thread quality here is what the rules are for. Keep it up.

4 4PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 1 other
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