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ForumsCompounding & FormulationNeedle gauge and dead space — need advice Page 2

Needle gauge and dead space — need advice

sarah_TO Wed, Jun 26, 2024 at 2:36 AM 14 replies 2,007 viewsPage 2 of 3
BethLabQueen
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Jun 26, 2024 at 5:16 AM#6
sarah_TO said:
Concentration choice is a precision decision, not a preference.

Ongoing cost tracking for dosing arithmetic — transparency for the community:

Monthly medication cost: $150
Supplies (syringes, BAC water, alcohol swabs): ~$8/month
Janoshik testing: ~$10/month (amortized quarterly)
Lab work: ~$50/month (amortized quarterly)
Total: ~$230/month

Compare to brand Wegovy at $1390/month without insurance. Compounded is roughly 85% cheaper for what I have found to be clinically equivalent medication.

3 6maya_sedona, stefan_berlin, Dr.EM_Chicago
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Dr.EM_Chicago
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Jun 26, 2024 at 6:18 AM#7

Following on from KevinCompounds — and this may be the naive question:

How to check the arithmetic without trusting a website calculator, since three calculators gave me three answers?

Last edited: Jun 26, 2024 at 10:18 AM
4 7matt_MKE, Dr.ReproEndo, lucas_SP_BR and 1 other
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jim_asheville
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Jun 26, 2024 at 7:20 AM#8
BethLabQueen said:
Ongoing cost tracking for dosing arithmetic — transparency for the community: Monthly medication cost: $150 Supplies (syringes, BAC water, alcohol…

For anyone reconstituting dosing arithmetic peptides: the water-to-powder ratio determines your concentration. Here's my reference:

Vial SizeBAC WaterConcentration0.25mg Dose
5mg2mL2.5mg/mL10 units
5mg2.5mL2mg/mL12.5 units
10mg2mL5mg/mL5 units
10mg3mL3.33mg/mL7.5 units

More water = easier to measure small doses but vial runs out faster. Find the balance that works for your dose.

5 8NurseAsh_DET, BenResearch_OR, MikeKY_noInsulin and 2 others
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sarah_TO
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Sep 2024
Toronto, CA
Jun 26, 2024 at 8:22 AM#9

Reporting back.

Follow-up: it was dead space. Switching to a low-dead-space fixed-needle syringe gave me the tenth dose back.

Last edited: Jun 26, 2024 at 12:22 PM
6 9carl_compliance, DanielChem_CHI, marco_milano and 3 others
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MikeKY_noInsulin
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Jun 26, 2024 at 1:20 PM#10
jim_asheville said:
For anyone reconstituting dosing arithmetic peptides: the water-to-powder ratio determines your concentration.

Agreeing with jim_asheville, and the qualification matters more than the agreement. The arithmetic is right and one caveat matters: a U-40 syringe changes the markings, not the volumes. If someone hands you U-40 and you read it as U-100 you will be 2.5 times out, and that error has a direction — it is always an overdose.

26 1bbq_ray_KC, oliver_london, tane_welly and 23 others
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